1. Intralesional and sub-Tenon's infusion of corticosteroids for treatment of refractory periorbital and orbital capillary haemangioma.
- Author
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Friling, R., Axer-Siegel, R., Ben-Amitai, D., Goldenberg-Cohen, N., Weinberger, D., and Snir, M.
- Subjects
CORTICOSTEROIDS ,TUMORS ,INFANTS ,TRIAMCINOLONE ,EXOPHTHALMOS ,STEROID drugs ,THERAPEUTICS - Abstract
PurposeTo evaluate the effect of combined intralesional and sub-Tenon's administration of corticosteroids for the treatment of refractory periocular and orbital capillary haemangioma in a retrospective, non-comparative study.MethodsSeven infants with resistant periorbital and orbital capillary haemangioma who attended our tertiary centre from 2000 to 2005 were treated with an intralesional injection of a mixture of betamethasone 6 mg/cc and triamcinolone 10 mg/cc, by body weight, together with sub-Tenon's infusion of betamethasone 6 mg/cc and triamcinolone 40 mg/cc of a volume of 1 cc, close to the orbital lesion, in the same session. Visual axis, proptosis, pre- and post-treatment changes in four refractive parameters, and parental satisfaction were evaluated.ResultsNone of the babies had proptosis or visual axis obstruction after treatment. Mean spherical power decreased by 22.7% (P=0.06). Mean spherical equivalent decreased in 34%, but the difference was not statistically significant (P=0.09). No early or late ocular side effects were observed. Mean intraocular pressure results were normal before and immediately after treatment, and during the follow-up period. Parental satisfaction score during follow-up was 9/10. Mean time to improvement was 96.43±58.3 days.ConclusionsCombined local corticosteroid administration by posterior sub-Tenon’s infusion and intralesional injection in babies with extensive capillary haemangioma is associated with a satisfactory anatomical and functional outcome and there were no ophthalmic side effects.Eye (2009) 23, 1302–1307; doi:10.1038/eye.2008.300; published online 7 November 2008 [ABSTRACT FROM AUTHOR]
- Published
- 2009
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