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1. Synthesis and cytotoxic activities of novel bergenin derivatives.

Author

Liu, Na-Na, Bao, Fu-Kai, Chen, Jing-Bo, Zeng, Xiang-Hui, Chi, Shui-Jing, and Liu, Jian-Ping

Abstract

A series of novel bergenin derivatives based on alcoholic hydroxyl group(s) modifications have been designed, synthesized and their cytotoxic activities against two human cancer cell lines including K562 and HL60 were evaluated. Over half of the tested derivatives, mainly with nitrogen containing moieties, displayed strong activities against K562 and HL60 cell lines. Graphical Abstract: [Figure not available: see fulltext.] [ABSTRACT FROM AUTHOR]

Published
2014
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