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Antibiotics abuse has caused increased bacterial resistance, which severely limits the application of antibiotics to the treatment of bacterial infections. Therefore, it is urgent to develop new antibacterial drugs through other sources. Dracontomelon dao (Blanco) Merr. & Rolfe (Ren Mianzi in Chinese) is a traditional medicinal material derived from Anacardiaceae with a long history of treating various infectious diseases, such as decubitus and skin ulcers. Recent research has indicated that different extracts from the leaves of D. dao, especially the ethyl acetate (EtOAc) fraction containing flavonoids and phenolic acids, exhibit potent antibacterial activities. In this research, the combined anti-drug-resistant bacterial activities of these active ingredients were investigated. Six samples (S1–S6) were obtained from the EtOAc fraction of D. dao leaves. Microcalorimetric measurements and principal component analysis were performed on the in vitro samples. The results showed that all six samples had notable antibacterial activities. Specifically, sample S6 exhibited a prominent antibacterial effect, with an IC50 value of 84.3 μg mL−1, which was significantly lower than that of other samples. The relative contents of main flavonoids and phenolic acids in S6 sample were confirmed by UPLC/Q-TOF-MS. In conclusion, sample S6 from the EtOAc fraction of D. dao leaves could be used as a potential antimicrobial resource in the treatment of infectious diseases. This work provides an insight into the effect of traditional Chinese medicine on drug-resistant bacteria. Moreover, the purification and characterization of the chemical compounds from the sample S6 deserve further analysis. [ABSTRACT FROM AUTHOR]

Iodination of meta-iodobenzylguanidine was carried out at optimum conditions. The labeling yield at these conditions was more than 95%. Further purification of the prepared compound increased the radiochemical purity to more than of 99.5%, this high purity was revealed in the quality of the images resulting from the use of the prepared compounds. [ABSTRACT FROM AUTHOR]

New limits on [sup 48]Caβ[sup –] and β[sup –]β[sup –] decays to excited states of [sup 48]Ti have been obtained using a 400cm[sup 3] low-background HPGe detector and an external source of 24.558g enriched CaF[sub 2] powder (9.822g of [sup 48]Ca). The limits for β[sup –] decay to the 6[sup +] ground state and excited 5[sup +] and 4[sup +] states in [sup 48]Sc are 1.6×10[sup 20] yr, 2.5×10[sup 20] yr, and 1.9×10[sup 20] yr at the 90% confidence level. For the β[sup –]β[sup –] decay to [sup 48]Ti, the limits to the first 2[sup +], second 2[sup +], and first 0[sup +] excited states are 1.8×10[sup 20] yr, 1.5×10[sup 20] yr, and 1.5×10[sup 20] yr, again at the 90% confidence level. © 2002 MAIK “Nauka / Interperiodica”. [ABSTRACT FROM AUTHOR]

Examines the process of emulsion crystallization as an alternative method for purifying organic compounds. Conventional method of purifying organic compounds; Use of the alternate method to purify mixtures of meta- and para-chloronitrobenzene below their eutectic temperature; Potential of emulsion crystallization in breaking the eutectic.

The article discusses the characterization of the olfactory receptors in mice which are used to attract female mice by male counterparts. It mentions that fractionation and purification of compounds through high performance liquid chromatography bioassays revealed that tetradecen-1-ol chemical compound present in urine of male mice is responsible for attraction of female mice. It highlights that olfactory receptors of mice are also used for detection of volatile chemicals in environment.

The Granat-2 M growth facility has been updated for synthesizing different quartz glasses by the 'gas - vacuum in vacuum' scheme. Its prototype is a commercial facility used for floating ultrapure monomineral and doped quartz glasses by the KS-4 V glass production technology. [ABSTRACT FROM AUTHOR]

The article focuses on the separation and purification of daphnetin, daphnodorin B, p-hydroxybenzoic acid, and daphnodorin D 1 in Daphne odora var. Margirmt plant through high-speed counter-current chromatography (HSCCC). It explains that Daphne odora var. Margirmt is a flower and medical plant from the family of Thymelaeaceae. It cites how the dried plant was chopped into small pieces and extracted with a solvent mixture that composed of 95% ethyl acetate and ethanol.

A process is described for removing carbon-containing impurities from hydrogen with the use of an electrical discharge. Hydrogen purified by this process contains no more than 0.1 ppm carbon. [ABSTRACT FROM AUTHOR]

The article cites a study which pioneers in building a complex organic molecule which did not involve intermediate purification steps. A team led by Romano Orru has synthesized a complex drug-like compound out of novel molecular fragments through a three-stage, purification-independent process. The experiment's 24% yield is noted remarkable for a nine-bonded chemical synthesis.