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This Special Issue presents the outcomes from the 23rd African Association of Insect Scientists' Conference held in Cote D'Ivoire, in connection with similar initiatives within and outside Africa. Over 65 scientific papers from several countries, worldwide, were submitted, of which about 40 were accepted and published. The issue focused on new advances in the value chain of edible insects in Africa and beyond. An innovative light-emitting diode technology for mass harvesting of edible grasshopper has been developed. The nutrient composition of insects such as the desert locust has been evaluated. Organic waste streams have been found to affect insect productivity and nutritional value. Insect-based feed increases the nutritional quality of poultry meat. Conventional processing methods reduce microbiological hazards in edible insects. Bioaccumulation of heavy metals, excessive microbial loads and pesticides residues threaten safety of some edible insects, if quality control measures are not developed. Climate change will impede availability of edible insects; hence, necessitating upscaling of mass production technologies and sound conservation practices. Safety and hygiene, on the other hand, hamper the acceptability of insects as food and/or feed, particularly in developed countries. Food fortification with insects and isolation of bioactive compounds from them are new highlights in the Special Issue, which were previously under-explored in Africa. The application of modern food processing technology in the development of new products and the medicinal or commercial value derivable from edible insects and their therapeutic functions are excellent opportunities for expanding the sector. Since disgust factors exist, mass sensitisation on the benefits of consuming insects and insect-based products is a must. We believe that the new frontiers on insects for food, feed and other uses that have been presented in this special issue will undoubtedly stimulate more debates and collaborations in the sector within Africa and beyond. [ABSTRACT FROM AUTHOR]