1. Cystatin F a potential diagnostic biomarker in acute promyelocytic leukemia.
- Author
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Palani, Hamenth Kumar, Ganesan, Saravanan, Balasundaram, Nithya, Venkatraman, Arvind, Kulkarni, Uday, Korula, Anu, Nair, Sukesh C, Mani, Thenmozhi, Balasubramanian, Poonkuzhali, Abraham, Aby, Puttamallesh, Vinuth N, Gowda, Harsha, and Mathews, Vikram
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ACUTE promyelocytic leukemia , *ARSENIC trioxide , *BIOMARKERS - Abstract
A letter published in the Annals of Hematology discusses the need for a diagnostic test with a short turnaround time for acute promyelocytic leukemia (APL). The authors conducted a proteomic analysis to identify a unique protein biomarker in APL. They found that cystatin F, a secretory protein found in extracellular space and body fluids, was significantly overexpressed in APL cells compared to other types of leukemia and healthy control cells. The authors suggest that cystatin F could be a potential biomarker for the rapid diagnosis of APL and the initiation of appropriate therapies. [Extracted from the article]
- Published
- 2024
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