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Your search keyword '"Murata, Mitsuru"' showing total 15 results
Start Over Author "Murata, Mitsuru" Publisher springer japan
15 results on '"Murata, Mitsuru"'

1. Diagnostic and treatment guidelines for thrombotic thrombocytopenic purpura (TTP) 2017 in Japan

Author

Matsumoto, Masanori, Fujimura, Yoshihiro, Wada, Hideo, Kokame, Koichi, Miyakawa, Yoshitaka, Ueda, Yasunori, Higasa, Satoshi, Moriki, Takanori, Yagi, Hideo, Miyata, Toshiyuki, Murata, Mitsuru, and For TTP group of Blood Coagulation Abnormalities Research Team, Research on Rare and Intractable Disease supported by Health, Labour, and Welfare Sciences Research Grants

Published
2017
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14. Reference guide for the diagnosis of adult primary immune thrombocytopenia, 2023 edition.

Author

Kashiwagi H, Kuwana M, Murata M, Shimada N, Takafuta T, Yamanouchi J, Kato H, Hato T, and Tomiyama Y

Subjects
Adult, Humans, Blood Platelets, Platelet Count, Thrombopoietin, Purpura, Thrombocytopenic, Idiopathic, Anemia, Aplastic diagnosis, Thrombocytopenia diagnosis, Leukopenia
Abstract

Primary immune thrombocytopenia (ITP) is an autoimmune disorder characterized by isolated thrombocytopenia due to accelerated platelet destruction and impaired platelet production. Diagnosis of ITP is still challenging because ITP has been diagnosed by exclusion. Exclusion of thrombocytopenia due to bone marrow failure is especially important in Japan because of high prevalence of aplastic anemia compared to Western countries. Hence, we propose a new diagnostic criteria involving the measurement of plasma thrombopoietin (TPO) levels and percentage of immature platelet fraction (RP% or IPF%); 1) isolated thrombocytopenia with no morphological evidence of dysplasia in any blood cell type in a blood smear, 2) normal or slightly increased plasma TPO level (< cutoff), 3) elevated RP% or IPF% (> upper limit of normal), and 4) absence of other conditions that potentially cause thrombocytopenia including secondary ITP. A diagnosis of ITP is made if conditions 1-4 are all met. Cases in which criterion 2 or 3 is not met or unavailable are defined as "possible ITP," and diagnosis of ITP can be made mainly by typical clinical course. These new criteria enable us to clearly differentiate ITP from aplastic anemia and other forms of hypoplastic thrombocytopenia and can be highly useful in clinical practice for avoiding unnecessary bone marrow examination as well as for appropriate selection of treatments., (© 2023. The Author(s).)

Published
2024
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15. Reference guide for management of adult immune thrombocytopenia in Japan: 2019 Revision.

Author

Kashiwagi H, Kuwana M, Hato T, Takafuta T, Fujimura K, Kurata Y, Murata M, and Tomiyama Y

Subjects
Adrenal Cortex Hormones administration & dosage, Humans, Japan, Receptors, Thrombopoietin agonists, Rituximab therapeutic use, Splenectomy, Thrombocytopenia diagnosis, Thrombocytopenia immunology, Thrombocytopenia pathology, Patient Care Management, Practice Guidelines as Topic standards, Thrombocytopenia therapy
Published
2020
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