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Mucous membrane pemphigoid is a chronic autoimmune disease that mainly affects mucous membranes. Skin lesions occur in 10–43% of patients. The conjunctiva is involved in about 70% of patients. The component of the disease that affects the conjunctiva, regardless of involvement of nonocular sites, is commonly called ocular cicatricial pemphigoid. It is a bilateral, asymmetric, sight-threatening disease characterized by progressive conjunctival cicatrization associated with trichiasis, eyelid entropion, symblepharon, secondary corneal neovascularization, and scarring. It is characterized by IgG, IgA, or C3 (complement component) deposition in a linear fashion along the epithelial basement membrane zone. The disease usually presents between the ages of 30 and 90 years; it affects males twice as often as females.