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Your search keyword '"SCHIZOAFFECTIVE DISORDER"' showing total 108 results
Start Over Descriptor "SCHIZOAFFECTIVE DISORDER" Publisher springer berlin heidelberg
108 results on '"SCHIZOAFFECTIVE DISORDER"'

10. Schizoaffective Disorder

Author

Tsuang, M. T., Simpson, J. C., Fleming, J. A., Henn, Fritz, editor, Sartorius, Norman, editor, Helmchen, Hanfried, editor, and Lauter, Hans, editor

Published
2001
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17. Biological Marker Studies in Families

Author

Bondy, B., Ackenheil, M., Ertl, M., Giedke, H., König, P., Mundt, C., Sauer, H., Schleuning, G., Mendlewicz, Julien, editor, Hippius, Hanns, editor, Bondy, Brigitta, editor, Ackenheil, Manfred, editor, and Sandler, Merton, editor

Published
1992
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45. Association between serum lipid levels, osteoprotegerin and depressive symptomatology in psychotic disorders

Author

Ole A. Andreassen, Sherif M Gohar, Ragni Helene Mørch, Vidar M. Steen, Nils Eiel Steen, Trude Seselie Jahr Iversen, Ingrid Melle, and Ingrid Dieset

Subjects
Adult, Male, Psychosis, medicine.medical_specialty, Schizoaffective disorder, Comorbidity, Gastroenterology, 03 medical and health sciences, chemistry.chemical_compound, Young Adult, 0302 clinical medicine, Osteoprotegerin, Internal medicine, medicine, Humans, Pharmacology (medical), Biological Psychiatry, Depression (differential diagnoses), Triglycerides, Dyslipidemias, Inflammation, Original Paper, Positive and Negative Syndrome Scale, Cholesterol, business.industry, Norway, Depression, General Medicine, Cholesterol, LDL, medicine.disease, 3. Good health, 030227 psychiatry, Psychiatry and Mental health, Interleukin 1 Receptor Antagonist Protein, C-Reactive Protein, chemistry, Psychotic Disorders, Dyslipidemia, Schizophrenia, Receptors, Tumor Necrosis Factor, Type I, Bipolar, Cytokines, Female, business, 030217 neurology & neurosurgery
Abstract

Although the relationship between positive and negative symptoms of psychosis and dyslipidemia has been thoroughly investigated in recent studies, the potential link between depression and lipid status is still under-investigated. We here examined the association between lipid levels and depressive symptomatology in patients with psychotic disorders, in addition to their possible inflammatory associations. Participants (n = 652) with the following distribution: schizophrenia, schizophreniform and schizoaffective disorder (schizophrenia group, n = 344); bipolar I, II, NOS, and psychosis NOS (non-schizophrenia group, n = 308) were recruited consecutively from the Norwegian Thematically Organized Psychosis (TOP) Study. Clinical data were obtained by Positive and Negative Syndrome Scale (PANSS), and Calgary Depression Scale for Schizophrenia (CDSS). Blood samples were analyzed for total cholesterol (TC), low-density lipoprotein (LDL), triglyceride (TG), C-reactive protein (CRP), soluble tumor necrosis factor receptor 1(sTNF-R1), osteoprotegerin (OPG), and interleukin 1 receptor antagonist (IL-1Ra). After adjusting for age, gender, BMI, smoking, and dyslipidemia-inducing antipsychotics, TC and LDL scores showed significant associations with depression [β = 0.13, p = 0.007; β = 0.14, p = 0.007], and with two inflammatory markers: CRP [β = 0.14, p = 0.007; β = 0.16, p = 0.007] and OPG [β = 0.14, p = 0.007; β = 0.11, p = 0.007]. Total model variance was 17% for both analyses [F(12, 433) = 8.42, p

Published
2018

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