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Liposuction is one of the most commonly performed aesthetic procedures worldwide and has caught the imagination of surgeons, patients and manufacturers alike during its brief history. The latter are now increasingly marketing direct to patients; however, liposuction is not a panacea for obesity and patients may not always fully appreciate this. On the other hand, eminently satisfactory outcomes are achievable with careful patient selection when undertaken by appropriately trained surgeons using optimally selected technologies. With such a range of techniques, technologies and recent advances, this chapter briefly reviews some of the pertinent scientific evidence.