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378 results on '"Marx, Gernot"'

2. Volumentherapie

Author

Simon, Tim-Philipp, Zacharowski, Kai, Marx, Gernot, Marx, Gernot, editor, Muhl, Elke, editor, Zacharowski, Kai, editor, and Zeuzem, Stefan, editor

Published
2024
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3. Sepsis

Author

Schürholz, Tobias, Marx, Gernot, Marx, Gernot, editor, Muhl, Elke, editor, Zacharowski, Kai, editor, and Zeuzem, Stefan, editor

Published
2024
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5. Sepsis

Author

Schürholz, Tobias, primary and Marx, Gernot, additional

Published
2023
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7. THALEA

Author

Marx, Gernot, Marx, Gernot, editor, Rossaint, Rolf, editor, and Marx, Nikolaus, editor

Published
2021
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10. Key summary of German national treatment guidance for hospitalized COVID-19 patients: Key pharmacologic recommendations from a national German living guideline using an Evidence to Decision Framework (last updated 17.05.2021)

Author

Malin, Jakob J., Spinner, Christoph D., Janssens, Uwe, Welte, Tobias, Weber-Carstens, Steffen, Schälte, Gereon, Gastmeier, Petra, Langer, Florian, Wepler, Martin, Westhoff, Michael, Pfeifer, Michael, Rabe, Klaus F., Hoffmann, Florian, Böttiger, Bernd W., Weinmann-Menke, Julia, Kersten, Alexander, Berlit, Peter, Krawczyk, Marcin, Nehls, Wiebke, Fichtner, Falk, Laudi, Sven, Stegemann, Miriam, Skoetz, Nicole, Nothacker, Monika, Marx, Gernot, Karagiannidis, Christian, and Kluge, Stefan

Published
2022
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12. Zukunftsvisionen

Author

Marx, Gernot, Dellweg, Dominic, Bickenbach, Johannes, Bickenbach, Johannes, editor, Marx, Gernot, editor, Dreher, Michael, editor, and Schönhofer, Bernd, editor

Published
2018
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16. Correction to: Key summary of German national treatment guidance for hospitalized COVID‑19 patients: Key pharmacologic recommendations from a national German living guideline using an Evidence to Decision Framework (last updated 17.05.2021)

Author

Malin, Jakob J., Spinner, Christoph D., Janssens, Uwe, Welte, Tobias, Weber-Carstens, Steffen, Schälte, Gereon, Gastmeier, Petra, Langer, Florian, Wepler, Martin, Westhoff, Michael, Pfeifer, Michael, Rabe, Klaus F., Hoffmann, Florian, Böttiger, Bernd W., Weinmann-Menke, Julia, Kersten, Alexander, Berlit, Peter, Krawczyk, Marcin, Nehls, Wiebke, Fichtner, Falk, Laudi, Sven, Stegemann, Miriam, Skoetz, Nicole, Nothacker, Monika, Marx, Gernot, Karagiannidis, Christian, and Kluge, Stefan

Published
2022
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17. Volumentherapie

Author

Simon, Tim-Philipp, Zacharowski, Kai, Marx, Gernot, Marx, Gernot, editor, Muhl, Elke, editor, Zacharowski, Kai, editor, and Zeuzem, Stefan, editor

Published
2015
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19. Telemedizin

Author

Marx, Gernot, Deisz, Robert, Marx, Gernot, editor, Muhl, Elke, editor, Zacharowski, Kai, editor, and Zeuzem, Stefan, editor

Published
2015
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21. Telemedizin

Author

Marx, Gernot, primary, Gilger, Katrin, additional, and Deisz, Robert, additional

Published
2019
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22. Correction to: Incidence of severe sepsis and septic shock in German intensive care units: the prospective, multicentre INSEP study

Author

Marx, Gernot, Litmathe, Jens, Schulz, Jörg B., Dafotakis, Manuel, Möllhoff, Thomas, Stalljohann, Carolin, Engels, Jonas, Sauerzapfe, Barbara, Stolzenberg, Barbara, Jonas, Engels, Möllhoff, Thomas, Carolin, Stalljohann, Thorben, Beeker, Gernot, Marx, Melanie, Schäfer, Tobias, Schürholz, Ertunc, Altiok, Marx, Nikolaus, Alexander, Kersten, Hannah, Dückers, Alexander, Koch, Trautwein, Christian, Scharf, Alexander, Kreuzer, Ilse, Jaschinski, Ulrich, Kreuzer, Ilse, Jaschinski, Ulrich, Niklas, Markus, Kulzer, Michael, Schlott, Martin, Iberer, Thomas, Stella, Oelert, Thorsten, Löhr, Vandana, Pillai, Praeger, Damaris, Knebel, Fabian, Baumann, Gert, Rosseau, Simone, Schlenk, Florian, Hoffmeister, Bodo, Compton, Friederike, Hoffmann, Clemens, Rademacher, Sibylle, Vietzke, Michael, Jörres, Achim, Meisel, Andreas, Hotter, Benjamin, Mengel, Annerose, Goldmann, Anton, Nöther, Frank, Keh, Didier, Schmidt, Katrin, Angermair, Stefan, Kaffarnik, Magnus, Bubser, Florian, Gummelt, Immo, Vedder, Ina, Bach, Friedhelm, Winter, Markus, Weißer, Frank, Roederer, Marc, Martini, Stefan, Bergmann, Lars, Adamzik, Michael, Baumann, Andreas, Wolf, Britta, Zahn, Peter K., Lehnhardt, Marcus, Daigeler, Adrien, Andreas, Andreas Hohn, Reinhold, Katrin, Adolf, Michael, Altenbeck, Nicole, Gussone, Christoph, Dietrich, Johannes Wolfgang, Köditz, Roland, Putensen, Christian, Schewe, Jens-Christian, Muders, Thomas, Soukup, Jens, Skitek, Kornel, Geisser, Wolfgang, Alber, Andreas, Düthorn, Ludwig, Demund, Josef, Düthorn, Ludwig, Criegern, Isabel v., Nowak, Andreas, Morgenstern, Toralf, Gliniorz, Christoph, Meisner, Michael, Dexel, Melanie, Schütte, Jan Karl, Huppertz-Thyssen, Markus H., Schröder, Stefan, Kowalzik, Ralf, Guel, Cansu, Terhorst, Rainer, Nießen, Peter, Hauschild, Rolf, Mutzek, Elisabeth-Maria, Kogelmann, Klaus, Drüner, Matthias, Jarczak, Dominik, Forster, Christian, Willam, Carsten, Eckardt, K. U., Clemenz, Rüdiger, Siemonsen, Sven, Pauschinger, Matthias, Baumgärtel, Matthias, Muschner, Dorothea, Christ, Michael, Wenzl, Martin, Höhl, Rainer, Junger, Axel, Wöhrle, Armin, Kanthak, Henry, Leschke, Matthias, Kanthak, Henry, Wöhrle, Armin, Leschke, Matthias, Kessler, Paul, Souquet, Jochen, Holfeld, Andreas, Habler, Oliver, Thörner, Markus, Vogt, Oliver, Meybohm, Patrick, Zacharowski, Kai, Lindau, Simone, Lenk, Marcus, Weis, Florian, Schubert, Hermann, Kemnitz, Jürgen, Reckort, Sven, Weikert, Martina, Sudhues, Ulrich, Möller, Stefan, Stefan, Pinger, Domke, Andrea, Wiesenack, Christoph, Schmidt, Florian, Döbel, Kai-Uwe, Moerer, Onnen, Schäper, Jörn, Kernchen, Andrea, Gründling, Matthias, Bollmann, Jan, Kuhn, Sven-Olaf, Kemming, Gregor, Einfeld, Carsten, Sommerer, Thomas, Kemming, Gregor, Einfeld, Carsten, Sommerer, Thomas, Köntges, Philipp, Hinz, Burkhard, Jauch, Lars-Oliver, Selonke, Lutz, Kluge, Stefan, Nierhaus, Axel, de Heer, Geraldine, Gruß, Marco, Köhler, Katja, Brinkmann, Alexander, Fuchs, Thomas, Köberer, Andreas, Geuting, Markus, Weigt, Henry, Baltus, Thomas, Scheltz, Claudia, Bloos, Frank, Reinhart, Konrad, Jegen, Rudolf, Flucht, Marcus, Jürgen, Gburek, Flucht, Marcus, Jegen, Rudolf, Stumm, Anne, Rossenbach, Jannik, Stumm, Anne, Haller, Mathias, Stumm, Anne, Rossenbach, Jannik, Lynch, John, Kempkens, Martin, Buechner, Volkmar, Molitor, Dieter, Klasen, Gerda, Rahmen, Bruno, Muhr, Petra, Canaviri, Patricia, Fiedler, Fritz, Lutz, Jürgen, Kaiser, Marc, Klünter, Simon, Krep, Henning, Anders, Helge, Aduckathil, Sanjay, Sakka, Samir, Reessing, Jan Hinnerk, Aabaid, Sabrina, Löbe, Mathias, Bogatsch, Holger, Löffler, Marcus, Engels, Christoph, Molter, Gerd Peter, Stunz, Michael, Mitrenga, Anja, Geldner, Götz, Bürle, Monica, Klasen, Robert, Werner, Steffanie, Wilhelm, Wolfram, Silke, Frenzel, Juliane, Illert, Jana, Schuttpelz, Briegel, Josef, Möhnle, Patrick, Knorr, Adrian, Hartl, Wolfgang, Ney, Ludwig, Stemmler, Hans-Joachim, Pfister, Hans-Walter, Angstwurm, Matthias, Frey, Lorenz, Irlbeck, Michael, Huge, Volker, Weis, Marion, Kilger, Erich, Hofmann-Kiefer, Klaus, Felbinger, Thomas, Kaufmann, Ines, Goeschl, Julia, Brettner, Franz, Hamm, Heiner, Eife, Claudia, Peckelsen, Claus, Findeisen, Michael, Schmidt-Schridde, Patrick, Kuner, Andreas, Walz, Thomas, Kuner, Barbara, Schrauzer, Thomas, Nentwich, Jens, John, Stefan, Byhahn, Christian, Kretschmer, Thomas, Bergold, Martin N., Weyland, Andreas, Jelschen, Florian, Diers, Anja, Knebel, Frieder G., Kupfer, Thomas, Oppert, Michael, Rohde, Steffen, Möllemann, Angela, Oehmichen, Uwe, Renner, Theresa, Bone, Hans-Georg, Freyhoff, Jörg, Holst, Dana, Birken, Thomas, Henschel, Jörg, Gloger, Martin, Brock, Peter, Klösel, Stephan, Albuszies, Gerd, Schumacher, Detlef, Meierhenrich, Rainer, Schöpp, Alexej, Kuhn, Harald, Riessen, Reimer, Haap, Michael, Ziegler, Silvia, Fastnacht-Böttcher, Jana, Schröder, Rolf Jürgen, Weiss, Manfred, Frank, Katrin, Georgieff, Michael, Weiss, Manfred, Barth, Eberhard, Bracht, Henrik, Ehmcke, Heidrun, Francke, Astrid, Ott, Stefan, Köpcke, Jens, Meyer, Andreas, Jokiel, Gunnar, Freund, Thomas, Schick, Guido, Karassimos, Evagelos, and SepNet Critical Care Trials Group

Published
2017
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23. Diagnose und Therapie der Sepsis

Author

Schürholz, Tobias, Marx, Gernot, Burchardi, Hilmar, editor, Larsen, Reinhard, editor, Marx, Gernot, editor, Muhl, Elke, editor, and Schölmerich, Jürgen, editor

Published
2011
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24. Volumentherapie

Author

Simon, Tim-Philipp, Marx, Gernot, Burchardi, Hilmar, editor, Larsen, Reinhard, editor, Marx, Gernot, editor, Muhl, Elke, editor, and Schölmerich, Jürgen, editor

Published
2011
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27. Safety and tolerability of non-neutralizing adrenomedullin antibody adrecizumab (HAM8101) in septic shock patients: the AdrenOSS-2 phase 2a biomarker-guided trial

Author

Laterre, Pierre-François, Pickkers, Peter, Marx, Gernot, Wittebole, Xavier, Meziani, Ferhat, Dugernier, Thierry, Huberlant, Vincent, Schuerholz, Tobias, François, Bruno, Lascarrou, Jean-Baptiste, Beishuizen, Albertus, Oueslati, Haikel, Contou, Damien, Hoiting, Oscar, Lacherade, Jean-Claude, Chousterman, Benjamin, Pottecher, Julien, Bauer, Michael, Godet, Thomas, Karakas, Mahir, Helms, Julie, Bergmann, Andreas, Zimmermann, Jens, Richter, Kathleen, Hartmann, Oliver, Pars, Melanie, Mebazaa, Alexandre, AdrenOSS-2 study participants, Castanares Zapatero, Diego, Collienne, Christine, Gérard, Ludovic, Hantson, Philippe, Montiel, Virginie, Berghe, Caroline, Dujardin, Marie-France, Gielens, Leslie, Renard, Suzanne, UCL - SSS/IREC/MEDA - Pôle de médecine aiguë, UCL - SSS/IREC/CARD - Pôle de recherche cardiovasculaire, UCL - SSS/IREC/PNEU - Pôle de Pneumologie, ORL et Dermatologie, and UCL - (SLuc) Service de soins intensifs

Subjects
medicine.medical_specialty, Randomization, Original, Adrecizumab (HAM8101), lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Critical Care and Intensive Care Medicine, Placebo, Antibodies, Monoclonal, Humanized, law.invention, Adrenomedullin, Randomized controlled trial, Double-Blind Method, law, Internal medicine, Septic shock, medicine, Humans, Enibarcimab, business.industry, Hazard ratio, Endothelial function, medicine.disease, Shock, Septic, Treatment Outcome, Tolerability, SOFA score, business, Biomarkers
Abstract

Purpose Investigate safety and tolerability of adrecizumab, a humanized monoclonal adrenomedullin antibody, in septic shock patients with high adrenomedullin. Methods Phase-2a, double-blind, randomized, placebo-controlled biomarker-guided trial with a single infusion of adrecizumab (2 or 4 mg/kg b.w.) compared to placebo. Patients with adrenomedullin above 70 pg/mL

Published
2021

33. Sepsis

Author

Schürholz, Tobias, primary and Marx, Gernot, additional

Published
2015
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38. Correction to: Key summary of German national treatment guidance for hospitalized COVID‑19 patients

Author

Malin, Jakob J., Spinner, Christoph D., Janssens, Uwe, Welte, Tobias, Weber-Carstens, Steffen, Schälte, Gereon, Gastmeier, Petra, Langer, Florian, Wepler, Martin, Westhoff, Michael, Pfeifer, Michael, Rabe, Klaus F., Hoffmann, Florian, Böttiger, Bernd W., Weinmann-Menke, Julia, Kersten, Alexander, Berlit, Peter, Krawczyk, Marcin, Nehls, Wiebke, Fichtner, Falk, Laudi, Sven, Stegemann, Miriam, Skoetz, Nicole, Nothacker, Monika, Marx, Gernot, Karagiannidis, Christian, and Kluge, Stefan

Subjects
Hospitalization, SARS-CoV-2, Practice Guidelines as Topic, Immunization, Passive, Correction, COVID-19, Humans, COVID-19 Serotherapy
Abstract

This executive summary of a national living guideline aims to provide rapid evidence based recommendations on the role of drug interventions in the treatment of hospitalized patients with COVID-19.The guideline makes use of a systematic assessment and decision process using an evidence to decision framework (GRADE) as recommended standard WHO (2021). Recommendations are consented by an interdisciplinary panel. Evidence analysis and interpretation is supported by the CEOsys project providing extensive literature searches and living (meta-) analyses. For this executive summary, selected key recommendations on drug therapy are presented including the quality of the evidence and rationale for the level of recommendation.The guideline contains 11 key recommendations for COVID-19 drug therapy, eight of which are based on systematic review and/or meta-analysis, while three recommendations represent consensus expert opinion. Based on current evidence, the panel makes strong recommendations for corticosteroids (WHO scale 5-9) and prophylactic anticoagulation (all hospitalized patients with COVID-19) as standard of care. Intensified anticoagulation may be considered for patients with additional risk factors for venous thromboembolisms (VTE) and a low bleeding risk. The IL-6 antagonist tocilizumab may be added in case of high supplemental oxygen requirement and progressive disease (WHO scale 5-6). Treatment with nMABs may be considered for selected inpatients with an early SARS-CoV-2 infection that are not hospitalized for COVID-19. Convalescent plasma, azithromycin, ivermectin or vitamin DFor COVID-19 drug therapy, there are several options that are sufficiently supported by evidence. The living guidance will be updated as new evidence emerges.

Published
2021

39. Key summary of German national treatment guidance for hospitalized COVID-19 patients

Author

Malin, Jakob J., Spinner, Christoph D., Janssens, Uwe, Welte, Tobias, Weber-Carstens, Steffen, Schälte, Gereon, Gastmeier, Petra, Langer, Florian, Wepler, Martin, Westhoff, Michael, Pfeifer, Michael, Rabe, Klaus F., Hoffmann, Florian, Böttiger, Bernd W., Weinmann-Menke, Julia, Kersten, Alexander, Berlit, Peter, Krawczyk, Marcin, Nehls, Wiebke, Fichtner, Falk, Laudi, Sven, Stegemann, Miriam, Skoetz, Nicole, Nothacker, Monika, Marx, Gernot, Karagiannidis, Christian, and Kluge, Stefan

Subjects
Original Paper, COVID-19 / SARS-CoV-2, COVID-19, SARS-CoV-2, Living guideline, Living meta-analysis, ddc
Published
2020

45. Hypertensiver Notfall

Author

Obermüller, Nicholas, Marx, Gernot, editor, Muhl, Elke, editor, Zacharowski, Kai, editor, and Zeuzem, Stefan, editor

Published
2024
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