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157 results on '"Klaas M"'

2. Planar, Stereoscopic, and Holographic PIV-Measurements of the In-Cylinder Flow of Combustion Engines

Author

van Overbrüggen, T., Bücker, I., Dannemann, J., Karhoff, D.-C., Klaas, M., Schröder, W., Boersma, Bendiks Jan, Series editor, Fujii, Kozo, Series editor, Haase, Werner, Series editor, Leschziner, Michael A., Series editor, Periaux, Jacques, Series editor, Pirozzoli, Sergio, Series editor, Rizzi, Arthur, Series editor, Roux, Bernard, Series editor, Shokin, Yurii I., Series editor, Klaas, Michael, editor, Pischinger, Stefan, editor, and Schröder, Wolfgang, editor

Published
2015
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6. Laparoscopic Rectopexy

Author

van der Zee, David C., Bax, Klaas M. A., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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8. Hand-assisted Colectomy

Author

van der Zee, David C., Bax, Klaas M. A., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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9. Intestinal Malrotation

Author

Bax, Klaas M. A., van der Zee, David C., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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13. Aortosternopexy for Tracheomalacia

Author

Bax, Klaas M. A., van der Zee, David C., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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14. Thoracoscopic Venous Vascular Access

Author

Bax, Klaas M. A., van der Zee, David C., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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17. Why Endoscopic Surgery?

Author

Bax, Klaas M. A., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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19. Fluid Mechanical Equilibrium Processes in a Multi-bifurcation Model

Author

Soodt, T., Henze, A., Boenke, D., Klaas, M., Schröder, W., Hirschel, Ernst Heinrich, editor, Schröder, Wolfgang, editor, Fujii, Kozo, editor, Haase, Werner, editor, van Leer, Bram, editor, Leschziner, Michael A., editor, Pandolfi, Maurizio, editor, Periaux, Jacques, editor, Rizzi, Arthur, editor, Roux, Bernard, editor, Shokin, Yurii I., editor, Klaas, Michael, editor, and Koch, Edmund, editor

Published
2011
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24. Esophageal Replacement with Jejunum in Children

Author

Klaas M. A. Bax

Subjects
medicine.medical_specialty, business.industry, Peptic, Anastomosis, medicine.disease, Surgery, Jejunum, medicine.anatomical_structure, Atresia, Accidental, otorhinolaryngologic diseases, Medicine, Ingestion, Reflux esophagitis, Esophagus, business
Abstract

Reconstruction of the esophagus in children, when a larger part of the esophagus is absent or has been destructed, is still a challenge [1–3]. The most important indications for such a reconstruction in children are esophageal atresia (EA, either as a primary reconstruction in pure EA or after failed anastomotic attempts in AE/TEF) or destruction of the esophagus by accidental or suicidal ingestion of a caustic substance. Occasionally a peptic stricture may require esophageal replacement as well. Patients with such indications differ significantly in terms of characteristics: Patients with EA are mostly newborns or infants. When the newborn cannot swallow properly for a prolonged period of time, feeding difficulties persist even after esophageal reconstruction [4]. Early restoration of the esophagus seems therefore important. In contrast patients with extensive esophageal strictures due to caustic injuries or reflux esophagitis are usually much older and have swallowed properly before.

Published
2017
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25. Cooperative Transport Mechanism and Proton-Coupling in the Multidrug Efflux Transporter Complex ArcAB-TolC

Author

Hi-jea Cha and Klaas M. Pos

Subjects
Chemistry, Antiporter, Biophysics, Inner membrane, Cooperativity, Periplasmic space, Membrane transport, Bacterial outer membrane, Efflux pump complex, Major facilitator superfamily
Abstract

Cooperativity and allostery within catalytically active protein complexes are important concepts for control of phenotypic outcome within a living system. In this chapter, the putative molecular determinants for cooperativity and allostery of a multi-subunit antibiotic efflux pump complex are discussed. While resisting multiple antibiotic stresses, Gram-negative bacteria deploy a network of single and multicomponent drug efflux pumps to reduce the concentration of the drugs in the cytoplasm and periplasm. The dual membrane setup imposes a particular challenge for transport of drugs from the cytoplasm to the medium, and current hypothesis describes a multistep transport path of drugs across the inner and outer membrane by the action of different drug efflux pumps. Drug transport from the cytoplasm to the periplasm is catalyzed by single component drug efflux systems belonging to the ABC-transporter superfamily, the Major Facilitator Superfamily (MFS), The Multi Antimicrobial Extrusion (MATE) Family, and the Small Multidrug Resistance (SMR) family. Transport from the periplasm across the outer membrane is catalyzed by a tripartite transport complex consisting of an inner membrane Resistance-Nodulation-cell Division (RND) transporter, an adaptor protein, and an outer membrane channel. Cooperative effects occur at multiple levels within this three component RND system: Anticipated allostery for binding of ligands (drugs and H+) at the level of the protomer, interdependence of the protomers within the trimer, and cooperative effects between the three components within the entire transport complex. The molecular determinants of multiple substrates binding at different sites within the inner membrane transporter and its coupling to H+ binding and transport are being described here for the paradigm tripartite transport machinery AcrAB-TolC from Escherichia coli. High resolution structures of the three components, the anticipated three component setup, and a multitude of biophysical and biochemical data are combined to address the overall molecular understanding of secondary H+/drug antiport. With focus on the inner membrane RND component, drug and H+ binding and transport cooperativity are exemplified by exploiting a mechanism based on binding change and the strict coupling to the influx of H+.

Published
2014
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27. Abdominal Trauma

Author

Pranikoff, Thomas, Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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29. Laparoscopic Cholecystectomy

Author

Muensterer, Oliver J., Georgeson, Keith E., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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34. Splenectomy

Author

Rescorla, Frederick J., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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38. Laparoscopic Liver Surgery

Author

Podevin, Guillaume, Leclair, Marc David, Grapin, Christine, Hameury, Frederic, Paineau, Jacques, Heloury, Yves, Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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41. Total Colectomy with J Pouch

Author

Saito, Jacqueline M., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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43. Laparoscopic Appendectomy in Children

Author

Steyaert, Henri, Valla, Jean-Stéphane, Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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50. Laparoscopic Pyloromyotomy

Author

MacKinlay, Gordon A., Barnhart, Douglas C., Bax, Klaas M. A., editor, Georgeson, Keith E., editor, Rothenberg, Steven S., editor, Valla, Jean-Stéphane, editor, and Yeung, C K, editor

Published
2008
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