Byline: C.J. Trapali (1), B.D. Thanopoulos (1) Keywords: Key words: Anomalous pulmonary artery -- Right ventricular contractility -- Infant Abstract: Anomalous origin of the right pulmonary artery from the ascending aorta (AORPA) with severe right ventricular dysfunction in a neonate was completely diagnosed by echocardiography. Cardiac catheterization was performed to explore further right ventricular dysfunction, which is extremely rare at this age. Following cardiac catheterization, the patient died. We suggest that in critically ill infants with the aforementioned condition surgical repair guided by modern echocardiography must be the chosen management. Author Affiliation: (1) Department of Pediatric Cardiology, P & A Kyriakou and Agia Sophia Children's Hospital, 115 27 Goudi, Athens, Greece, GR