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Abstract A new paradigm of electronic devices with bio-inspired features is aiming to mimic the brain’s fundamental mechanisms to achieve recognition of very complex patterns and more efficient computational tasks. Networks of electropolymerized dendritic fibers are attracting much interest because of their ability to achieve advanced learning capabilities, form neural networks, and emulate synaptic and plastic processes typical of human neurons. Despite their potential for brain-inspired computation, the roles of the single parameters associated with the growth of the fiber are still unclear, and the intrinsic randomness governing the growth of the dendrites prevents the development of devices with stable and reproducible properties. In this manuscript, we provide a systematic study on the physical parameters influencing the growth, defining cause-effect relationships for direction, symmetry, thickness, and branching of the fibers. We build an electrochemical model of the phenomenon and we validate it in silico using Montecarlo simulations. This work shows the possibility of designing dendritic polymer fibers with controllable physical properties, providing a tool to engineer polymeric networks with desired neuromorphic features.

On 6 February 2018 at 23:50 local time, a Mw 6.4 earthquake struck eastern Taiwan. We characterize the instantaneous surface ground motion and the permanent displacement induced by this event from continuous GPS data and SAR images within a short time after the mainshock. We use high-rate GPS positioning techniques to obtain epoch-by-epoch positions peak ground displacement to assess potential seismic damage. The maximum coseismic GPS horizontal displacement of about 450 mm trending to the northeast is observed at the station HUAL located on the hanging wall of the Milun fault. The PEPU located on the footwall of the Milun fault shows a coseismic horizontal displacement of 280 mm trending to the southwest and a coseismic uplift of about 70 mm. Moreover, ascending and descending tracks of ALOS-2 and Sentinel-1 SAR images are processed to estimate coseismic surface deformation along the line-of-sight (LOS) toward the satellite. Then, wide coverage from east-west and uplift components of surface deformation is fulfilled by combining the LOS displacement from ascending and descending interferograms. The main deformation area revealed by both GPS results and D-InSAR interferograms is concentrated around the Milun and Lingding faults. Significant uplift on the footwall of the northern Lingding Fault implies that the Milun fault and an unknown westdipping fault close to the Lingding fault were triggered. Both the two nodal planes of the Mw 6.4 Hualien event could be different with the kinematic behavior of the Milun fault and Lingding fault. Thus we suggest that slip on multiple faults was triggered during the 0206 event.

In the southernmost Longitudinal Valley (LV), Taiwan, we analyzed a dense GPS array composed of 10 continuous stations and 86 campaign-mode stations. By removing the effects of the four major earthquakes (one regional and three local) occurred during the 1992 - 2010 observation period, we derived a new horizontal velocity field in this area, which then allows better locating the surface traces of the major active faults, including the Longitudinal Valley Fault (LVF) system and the Central Range Fault, and characterizing the slip behaviors along the faults. Note that LVF reveals two sub-parallel strands in the study area: the Luyeh Fault to the west and the Lichi Fault to the east. Based on the results of strain analyses, including dilatation and shear strain, and projected vectors of station velocities across the major faults, we came to the following geological interpretations. During the inter-seismic periods, the surface deformation of the southernmost LV is mainly accommodated by the faulting on the two branches of the LVF; there is very little surface deformation on the Central Range Fault. The Luyeh River appears to act as a boundary to divide the LVF to behave differently to its northern and southern sides. The Lichi Fault reveals a change of slip kinematics from an oblique shearing/thrusting in the north to a nearly pure shearing with minor extension to the south. Regarding the slip behavior of the Luyeh Fault, it exhibits a creeping behavior in the north and a partially near-surface-locked faulting behavior in the south. We interpret that the two strands of the LVF merge together in the northern Taitung alluvial plain and turns to E-W trend toward the offshore area.

In order to provide a detailed vertical velocity field in southernmost Longitudinal Valley where shows a complex three-fault system at the plate suture between Philippine Sea plate and Eurasia, we conducted leveling and GPS measurements, compiled data from previous surveys and combined them into a single data set. We compiled precise leveling results from 1984 to 2009, include 5 E-W trending and one N-S trending routes. We calculated the GPS vertical component from 10 continuous stations and from 89 campaign-mode stations from 1995 to 2010. The interseismic vertical rates are estimated by removing the co- and post-seismic effects of major large regional and nearby earthquakes. A stable continuous station S104 in the study area was adopted as the common reference station. We finally establish a map of the interseismic vertical velocity field. The interseismic vertical deformation was mainly accommodated by creeping/thrusting along two east-dipping strands of the three-fault system: the Luyeh and Lichi faults. The most dominant uplift of 30 mm yr-1 occurs at the hanging wall of the Lichi fault on the western Coastal Range. However the rate diminishes away from the fault in the hanging wall. The Quaternary tablelands inside of the Longitudinal Valley reveals uplift with a rate of 5 - 10 mm yr-1. Outside of the tablelands, the rest of the Longitudinal Valley flat area indicates substantial subsidence of -10 to -20 mm yr-1. Finally, it appears that the west-dipping blind fault under the eastern side of the Central Range does not play a significant role on interseismic deformation with subsidence rate of -5 to -10 mm yr-1.

Purpose: Partial bladder outlet obstruction (PBOO) in rabbits causes free radical production through ischemia and reperfusion within the bladder smooth muscle and mucosa. We had previously shown that pretreatment of rabbits with a combination of α-lipoic acid (αLA) and coenzyme Q10 (CoQ) protected the bladder from contractile and metabolic dysfunctions mediated by PBOO. In this study, we examined the ability of pretreatment with αLA and CoQ combination in rabbits to protect the bladder from contractile damage mediated by either hydrogen peroxide (H(2)O(2)) or in vitro ischemia-reperfusion (I/R) which represents two in vitro models of oxidative damage., Methods and Materials: Eight adult male New Zealand white rabbits were pretreated with CoQ and αLA orally for four weeks. Eight adult male control rabbits were given vehicle. Eight full-thickness bladder strips were isolated from each of 4 treated and 4 control rabbit bladders, and a dose-response curve to H(2)O(2) (0.1-0.8%) was generated. Similarly, isolated strips of bladder from the remaining 4 control and 4 treated rabbits were subjected to 1 h of ischemia (no oxygen without glucose) followed by 2 h of incubation in oxygenated buffer with glucose. The effects on the contractile responses to field stimulation (FS) at 2, 8, and 32 Hz, carbachol, and potassium chloride (KCl) were determined., Results: H(2)O(2) reduced the contractile responses to KCl and carbachol to a significantly greater degree than to FS, whereas I/R reduced the contractile responses to FS to a significantly greater degree than to KCl and carbachol. Pretreatment of the rabbits with the combination of CoQ and αLA significantly protected the bladder from the damaging effects of I/R, but had virtually no effect on the damaging effects of H(2)O(2)., Conclusion: Although both H(2)O(2) and I/R are in vitro models of oxidative free radical damage to bladder smooth muscle, they have significantly different methods of action and different sensitivities to antioxidants.