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Digital technologies based on 3D models are always more used to document archaeological remains and obtain hypothetical reconstructions when these remains are more or less heavily damaged. This work addresses the case of remains of ancient musical instruments, and in particular the case study of a brass instrument from the Roman Empire period, found in Voghenza (Italy). The pieces composing the instrument were first digitized by means of a structured light system, then virtually restored and recomposed applying a on-purpose developed algorithm. Finally, some sounds coherent with the geometry of the reconstructed model were simulated using a physically-based synthesis approach.

Transcranial magnetic resonance-guided focused ultrasound is a recently introduced incisionless treating option for essential tremor and tremor-dominant idiopathic Parkinson disease. There is preliminary evidence that it may result in a promising effective treatment option for other movement disorders too. Here, we report on two patients with multiple sclerosis with medication refractory debilitating essential tremor comorbidity who successfully underwent unilateral Vim tcMRgFUS thalamotomy for tremor control. Patients' clinical condition and expanded disability status scale scores showed no changes during the 1-year follow-up period with no evidence of multiple sclerosis activity or progression.

We evaluated the combined use of transcranial random noise stimulation (tRNS) with the Graded Repetitive Arm Supplementary Program (GRASP) in sub-acute ischemic stroke patients suffering from arm impairment. Eighteen ischemic stroke patients with upper limb disability were randomly assigned to either the GRASP + tRNS or GRASP + Sham stimulation group. Fugl-Meyer Assessment-Upper extremity (FMA-UE) was performed to evaluate upper limb impairment before treatment (T0), after the last stimulation (T1) and after 30 days (T2). At T1 and T2, beneficial effects in the tRNS group correlated with better FMA-UE score than sham stimulation group (p

A lead medal attributed to Antonio Averlino known as Filarete, with a portrait of Caesar, is preserved in the Gabinetto Numismatico of the Museo Civico Correr of Venice. This unicum presents oxidation coatings on both sides, so it was included in a restoration project of the Foundation of the Venetian Civic Museums. Through the acquisition of the object with high resolution scanning it is possible characterize the changes caused by oxidation coating, identify the particular style and mapping at micrometer scale the areas of degradation. For this purpose, two different laser scanning instruments are used in order to compare different resolution and accuracy and to produce a multi resolution model. The medallion was also replicated using rapid prototyping with ZPrinter 450 machine.