1. Blood glucose monitoring in the normal population: the PREDICA study
- Author
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Nicola Napoli, Antonio Picardi, Rocky Strollo, Elisa Cipponeri, W. Macino, F. Carrano, V. Dell’Anna, Paolo Pozzilli, F. Costanza, Silvia Manfrini, and E. Di Stasio
- Subjects
Adult ,Blood Glucose ,Male ,medicine.medical_specialty ,Endocrinology, Diabetes and Metabolism ,Population ,Overweight ,Fasting glucose ,Young Adult ,Endocrinology ,Internal medicine ,Diabetes mellitus ,Diabetes Mellitus ,Internal Medicine ,medicine ,Humans ,education ,Settore BIO/10 - BIOCHIMICA ,Aged ,Blood glucose monitoring ,education.field_of_study ,medicine.diagnostic_test ,diabetes ,business.industry ,Blood Glucose Self-Monitoring ,Glucose Measurement ,Normal population ,General Medicine ,Middle Aged ,medicine.disease ,Early Diagnosis ,Diabetes screening ,Female ,medicine.symptom ,business - Abstract
In the PREdiction of DIabetes from CApillary blood glucose (PREDICA) study, we propose a novel approach based on multiple capillary blood glucose (CBG) measurements, assuming that weekly measurements performed for 2 months may be an efficient strategy to screen for diabetes. We studied 538 Caucasian subjects (247 men and 291 women) without a history of diabetes, consecutively recruited by 50 GPs from the Italian provinces of Rome and Frosinone. Subjects were asked to perform 8 fasting glucose and 8 post-prandial glucose measurements during a frame time of 2 months (Glucometer Accu-chek AVIVA Roche Diagnostics). Study subjects were 55 ± 9 years old (range 22-77 years of age), 50% were overweight and 16% obese. Fifty-eight percent of subjects have performed 13 to 16 CBG measurements during the study, 68% of subjects have performed at least 5 out of 8, both fasting and post-prandial measurements. Among 492 subjects who had at least two fasting measurements, 63.6% had normal glucose levels, 25.4% showed IFG, and 11.0% were diabetic. Considering post-prandial measurements, 74.2% had normal glucose levels, 23.0% had IGT, and 2.8% were diabetic. Combined IFG + IGT was detected in 7% of study subjects, while in 0.8% diagnosis of diabetes was confirmed with both fasting and post-prandial measurements. In this study, we found a high adherence to a novel screening strategy based on self-glucose monitoring in the general population. Our results show that multiple CBG measurements may represent a simple and efficient method for diabetes screening.
- Published
- 2010