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2. Salmonella brain abscess in a patient on chronic azathioprine therapy for myasthenia gravis: report of an unusual case and review of literature in the postantibiotic era.

Author

Soni CR, Kumar G, Bollu PC, Sahota P, and Litofsky NS

Subjects
Abscess diagnostic imaging, Abscess pathology, Anti-Infective Agents administration & dosage, Brain diagnostic imaging, Brain pathology, Ciprofloxacin administration & dosage, Drug Administration Schedule, Female, Headache etiology, Humans, Immunosuppression Therapy, Metronidazole administration & dosage, Middle Aged, Myasthenia Gravis drug therapy, Radiography, Salmonella Infections drug therapy, Salmonella Infections physiopathology, Abscess microbiology, Azathioprine administration & dosage, Brain microbiology, Immunosuppressive Agents administration & dosage, Myasthenia Gravis complications, Salmonella drug effects, Salmonella Infections etiology
Abstract

Focal intracranial infections caused by Salmonella species in adults are exceedingly uncommon. Structural brain injury with coexisting immunocompromised status appears to predispose adults to this rare manifestation of Salmonella infection. We report a case of Salmonella brain abscess in a patient with myasthenia gravis on chronic azathioprine therapy without any prior structural brain lesion. We reviewed world literature and discuss their analysis of Salmonella brain abscess in adult population in the postantibiotic era.

Published
2010
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