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Spatial mobility is a distinctive feature of human history and has important repercussions in many aspects of societies. Spatial mobility has always been a subject of interest in many disciplines, even if only mobility observable from traditional sources, namely migration (internal and international) and more recently commuting, is generally studied. However, it is the other forms of mobility, that is, the temporary forms of mobility, that most interest today's societies and, thanks to new data sources, can now be observed and measured. This contribution provides an empirical and data-driven reflection on human mobility during the COVID pandemic crisis. The paper has two main aims: (a) to develop a new index for measuring the attrition in mobility due to the restrictions adopted by governments in order to contain the spread of COVID-19. The robustness of the proposed index is checked by comparing it with the Oxford Stringency Index. The second goal is (b) to test if and how digital footprints (Google data in our case) can be used to measure human mobility. The study considers Italy and all the other European countries. The results show, on the one hand, that the Mobility Restriction Index (MRI) works quite well and, on the other, the sensitivity, in the short term, of human mobility to exogenous shocks and intervention policies; however, the results also show an inner tendency, in the middle term, to return to previous behaviours., Competing Interests: Conflict of interestThe authors have no relevant financial or non-financial interests to disclose., (© The Author(s) 2023.)

This paper offers an analysis of the supply of Airbnb accommodation in Rome, one of the main tourist destinations in the world, the third-largest city in Europe, by the number of Airbnb listings. The aim is to focus on the recent spatial trend of Airbnb listings, including the period of the COVID-19 pandemic, and highlight the main housing and socioeconomic characteristics of the neighbourhoods associated with a strong presence of Airbnb listings. The study is developed with quantitative methods and spatial regression (spatial lag and spatial error using OLS as a benchmark), based on data collected from the Inside Airbnb and Tomslee websites. In the period 2014-2019, the listing trend in Rome has been increasing in absolute numbers. After the start of the pandemic, the trend became negative, and the decline of Airbnb offerings is more substantial for shared accommodation. Airbnb supply is related to the distance from the city centre, the average income of the area, empty apartments, singles and the share of foreign residents coming from high-income countries. A signal of spatial diffusion of Airbnb listings emerges in the coastal area, even if they are increasingly concentrated in the historic centre, where there is a monoculture of short-term renting., (© The Author(s) 2022.)

Recent years have seen an increase in the use of retinal nerve fiber layer (RNFL) evaluation as an easy-to-use, reproducible, proxy-measure of brain structural abnormalities. Here, we evaluated RNFL thickness in a group of subjects with high functioning autism (HFA) or with Asperger Syndrome (AS) to its potential as a tool to study autism pathophysiology. All subjects underwent high-resolution spectral domain optical coherence tomography to evaluate RNFL thickness. HFA subjects presented with reduced global RNFL thickness compared both to AS subjects and controls. AS subjects showed a reduced nasal quadrant RNFL thickness compared to controls. Verbal-IQ/performance-IQ discrepancy correlated with RNFL thickness. Our data suggest that RNFL evaluation could help in the development of biological markers of autism pathophysiology.

Recent evidence points to white-matter abnormalities as a key factor in autism physiopathology. Using Diffusion Tensor Imaging, we studied white-matter structural properties in a convenience sample of twenty-two subjects with low-functioning autism exposed to long-term augmentative and alternative communication, combined with sessions of cognitive and behavioral therapy. Uncinate fasciculus structural properties correlated significantly with therapy length and early onset, as well as to clinical outcome, independently from IQ, age or symptoms severity at therapy onset. Moreover, adherence to therapy was linked with better clinical outcome and uncinate fasciculus structural integrity. The results point to the capability of a long-term rehabilitation of subjects with low-functioning autism to produce white-matter structural modifications, which could thus play a role in the rehabilitative outcome.