Search

The paper presents the results of the study of the effectiveness and safety of the use of systemic enzyme therapy with Wobenzym in the complex treatment of patients with hormone-dependent severe bronchial asthma. It was found that the inclusion in the complex basic therapy of severe hormone-dependent bronchial asthma systemic enzyme Wobenzyme accompanied by improving the parameters of the functional state of the bronchi, reducing circulating immune complexes, a steady increase in cortisol levels. The data obtained convince of the safety of the inclusion of the preparation of systemic enzyme therapy in the complex treatment of patients with severe hormone-dependent bronchial asthma, improving the effectiveness of basic therapy, improving control over the course of the disease, allow to develop indications for the appointment of Wobenzyme patients with severe bronchial asthma.

An experimental group of 45 nondescript white mice was selected for a study of the influence of systemic enzyme therapy on performance and ability to withstand intensive physical loads, as well as on production of main cytokines. The findings were compared to a control group of 45 mice who received placebo. The physical performance was assessed after 1, 2, and 3 weeks according to the length of test swimming in the aquarium with the attached load of 5% of the body mass. Findings indicate that systemic enzyme therapy led to increased performance and endurance with increased physical load in the experimental group after three weeks of therapy. The mice in the experimental group showed decreased levels of anti-inflammatory TNFα and IL - 1β. Other observed changes were within the error range. (Med. Immunol., vol. 10, N 6, pp 577-582) .