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Your search keyword '"Naomi Kato Simas"' showing total 4 results
Start Over Author "Naomi Kato Simas" Publisher sociedade brasileira de quimica
4 results on '"Naomi Kato Simas"'

1. In vitro effect of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+, K+-ATPase

Author

Anne Caroline Candido Gomes, Luzia da Silva Sampaio, Paulo André da Silva, Marcelo Einicker Lamas, Cassia Mônica Sakuragui, Cleber Bomfim Barreto Junior, Naomi Kato Simas, and Ricardo Machado Kuster

Subjects
Syngonium podophyllum, Araceae, Isoschaftoside, enzyme inhibition, renal Na+, K+-ATPase, Chemistry, QD1-999
Abstract

The present study aimed to investigate the in vitro effects of isoschaftoside isolated from Syngonium podophyllum on pig kidney Na+,K+-ATPase. The Na+, K+-ATPase activity was determined by colorimetric measurement of inorganic phosphate (Pi), resulting from ATP hydrolysis. Isoschaftoside significantly decreased the renal Na+, K+-ATPase activity at the highest concentration as well as at a lower concentration. Our work suggests that isoschaftoside is a promising compound for the treatment of hypertension.

Published
2014
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2. Flavonoids and a neolignan glucoside from Guarea macrophylla (Meliaceae)

Author

Cristiane Pereira, Cleber Bomfim Barreto Júnior, Ricardo Machado Kuster, Naomi Kato Simas, Cassia Mônica Sakuragui, Andrea Porzel, and Ludger Wessjohann

Subjects
Guarea macrophylla, dehydrodiconiferyl alcohol-4-β-D-glucoside, flavonoid glycosides, Chemistry, QD1-999
Abstract

This work describes the phytochemical study of the methanol extract obtained from leaves of Guarea macrophylla, leading to the isolation and identification of three flavonoid glycosides (quercetin 3-O-β-D-glucopyranoside, quercetin 3-O-b-D-galactopyranoside, kaempferol 7-O-β-D-glucopyranoside) and a neolignan glucoside, dehydrodiconiferyl alcohol-4-β-D-glucoside. All compounds were identified by a combination of spectroscopic methods (¹H, 1D, 2D NMR, 13C and UV), ESI-MS and comparison with the literature data. This is the first report of flavonoids in the genus Guarea and of a neolignan glucoside in the Meliaceae family.

Published
2012
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4. Produtos naturais para o controle da transmissão da dengue: atividade larvicida de Myroxylon balsamum (óleo vermelho) e de terpenóides e fenilpropanóides

Author

Ricardo Machado Kuster, Naomi Kato Simas, Sheila da Rocha Conceição, Celso Luiz Salgueiro Lage, Alfredo Martins de Oliveira Filho, and Elisangela da Costa Lima

Subjects
Chromatography, biology, Myroxylon balsamum, fungi, food and beverages, General Chemistry, Aedes aegypti, Fractionation, Sesquiterpene, biology.organism_classification, Terpenoid, Thin-layer chromatography, essential oil constituents, Hexane, lcsh:Chemistry, chemistry.chemical_compound, Chemistry, chemistry, lcsh:QD1-999, Lipophilicity, QD1-999, Nerolidol
Abstract

The bioassay-guided fractionation of the hexane extract obtained from the medicinal plant Myroxylon balsamum (red oil) was conducted in preparative thin layer chromatography on silica gel. The obtained fractions and some terpenoids and phenylpropanoids were assayed as larvicidal on third instar Aedes aegypti larvae, NPPN colony. The results indicate that the sesquiterpene nerolidol was the active constituent in the extract and that the sesquiterpenes were more active than the monoterpenes and phenylpropanoids utilized in this study. Lipophilicity seems to be an important property for the activity since the compounds with hydroxyl, carbonyl and methoxyl groups were less active. The results confirm also that essential oils can be a good tool for the control of dengue.

Published
2004

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