1. The association of selenium status with thyroid hormones and anthropometric values in dyslipidemic patients.
- Author
-
Carvalho, Roberta F., Rosa, Glorimar, Huguenin, Grazielle V. B., Luiz, Ronir R., Moreira, Annie S. B., and Oliveira, Glaucia M. M.
- Subjects
- *
SELENIUM in the body , *DYSLIPIDEMIA , *ANTHROPOMETRY , *THYROID hormones , *MICRONUTRIENTS , *NUTRITION , *CARDIOVASCULAR diseases - Abstract
Background: Selenium (Se) is an essential micronutrient that performs physiological functions in the metabolism of thyroid hormone and may have an association with anthropometric variables relevant to cardiovascular disease. Aim: To study the associations between Se status, thyroid hormones and anthropometric variables in dyslipidemic patients.Methods: Eighty-three patients were assessed in a cross-sectional study. Blood samples were analyzed for Se and thyroid hormones. Anthropometric measurements were taken, and dietary Se intake was investigated. Results: Mean plasma Se concentrations were low in the patients, at 88.7 ± 16.7 /¿g/L. Patients with plasma Se > 95 //g/L were found to have a higher body mass index (BMI) (30.74 ± 4.31 vs 27.68 ± 5.63 kg/m2, P = 0.02) and waist-to-height ratio (0.65 ± 0.05 v.v 0.59 ± 0.07, P = 0.003) when compared to those with concentrations between 80 and 94 /ig/L. Se intake associated positively with T,L/T4L ratio (r = 0.273; P= 0.03), BMI (r= 0.257, P= 0.04) and WC (r= 0.299, P= 0.02). Conclusion: The patients with the highest normal plasma Se concentrations were found to have increases in the anthropometric variables we investigated. There is a need for further study in order to elucidate these findings. Furthermore, we found a positive association between Se intake and the most metabolically active form of the thyroid hormones. [ABSTRACT FROM AUTHOR]
- Published
- 2015
- Full Text
- View/download PDF