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2 results on '"Vincent Colombie"'

1. Hydroxychloroquine in a G6PD-Deficient Patient with COVID-19 Complicated by Haemolytic Anaemia: Culprit or Innocent Bystander

Author

François Mastroianni, Vincent Colombie, Géraldine Claes, Axelle Gilles, Frédéric Vandergheynst, and Sammy Place

Subjects
haemolytic anaemia, g6pd deficiency, covid-19, sars-cov-2, Medicine
Abstract

Hydroxychloroquine has been used worldwide as a first-line treatment for patients hospitalized with COVID-19. Little is known about COVID-19 and its effects on patients with congenital red blood cell disorders. We report a case of haemolytic anaemia in a 32-year-old patient and a fortuitous highlighting of G6PD deficiency. We reviewed the literature to assess the risk of hydroxychloroquine use in this context.

Published
2020
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2. Hydroxychloroquine in a G6PD-Deficient Patient with COVID-19 Complicated by Haemolytic Anaemia: Culprit or Innocent Bystander

Author

Geraldine Claes, Sammy Place, François Mastroianni, Vincent Colombie, Axelle Gilles, and Frederic Vandergheynst

Subjects
Pediatrics, medicine.medical_specialty, 2019-20 coronavirus outbreak, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), lcsh:Medicine, Context (language use), Culprit, 03 medical and health sciences, 0302 clinical medicine, hemic and lymphatic diseases, Internal Medicine, medicine, Bystander effect, 030212 general & internal medicine, 030203 arthritis & rheumatology, Red blood cell disorders, haemolytic anaemia, business.industry, lcsh:R, Hydroxychloroquine, Articles, sars-cov-2, covid-19, g6pd deficiency, business, medicine.drug
Abstract

Hydroxychloroquine has been used worldwide as a first-line treatment for patients hospitalized with COVID-19. Little is known about COVID-19 and its effects on patients with congenital red blood cell disorders. We report a case of haemolytic anaemia in a 32-year-old patient and a fortuitous highlighting of G6PD deficiency. We reviewed the literature to assess the risk of hydroxychloroquine use in this context. LEARNING POINTS: A rapid drop in haemoglobin in COVID-19 patients should alert physicians to test for haemolytic anaemia and enzymopathies. Our review of the literature shows that use of hydroxychloroquine is safe in G6PD-deficient patients.

Published
2020

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