1. Position paper on the preparation of immune plasma to be used in the treatment of patients with COVID-19.
- Author
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Accorsi P, Berti P, de Angelis V, De Silvestro G, Mascaretti L, and Ostuni A
- Subjects
- Antibodies, Viral adverse effects, Blood Banks organization & administration, Blood Banks standards, Blood Donors legislation & jurisprudence, COVID-19, Europe, Humans, Immunization Schedule, Immunization, Passive adverse effects, Immunization, Passive standards, Informed Consent, Italy, Pandemics, SARS-CoV-2, COVID-19 Serotherapy, Antibodies, Viral therapeutic use, Betacoronavirus immunology, Coronavirus Infections therapy, Immunization, Passive methods, Plasma immunology, Pneumonia, Viral therapy
- Abstract
Passive immunotherapy with plasma derived from convalescent patients recovering from SARS-CoV-2 infection can be a promising approach in the treatment of COVID-19 patients. It is important that blood establishments are ready to satisfy requests for immune plasma by defining the requirements applicable to plasma donors and the standards for preparation, qualification, storage, distribution, and control of product use. This Position paper aims to give recommendations on the biological characteristics of a plasma preparation from convalescent donors and to support the evaluation of this therapeutic approach in more rigorous investigations.
- Published
- 2020
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