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Background: Artificial intelligence has recently shown remarkable success in analyzing medical images due to the rapid expansion of deep learning algorithms. Objective: Researchers in this study aimed to provide accurate diagnosis and classification of acute lymphoblastic leukemia by processing microscopic. This diagnosis approach is based on deep learning, which is the core of the clinical decision system. Material and Methods: A large number of pathological images related to acute lymphoblastic leukemia and healthy cells are chosen. The dataset CodaLab competition included 12,528 images of 4,037 healthy cells and 8,491 leukemic cells. Extracted critical features were used to classify acute lymphoblastic leukemia and healthy cells by a pre-trained network, i.e., VGG 16. From the total number of images, 80% (10022 numbers) were used as training data and 20% (2506 numbers) as test data. The activation for all layers except the last layer was the ReLU function. Adam was selected for the optimization function with a learning rate of 0.0001. The intelligent diagnostic system was created using the Java programming language. Results: The training accuracy of the VGG-16 is 97.41%, and the validation accuracy is 84.62%. Precision, recall, and F-measure related to leukemia class are 0.88, 0.91, and 0.90, respectively. VGG-16 was used as the processing core in the decision support system. Conclusion: This system in medical centers is helpful for purposes such as timely diagnosis, reducing patient hospital stay and treatment costs, and improving the patient referral system. [ABSTRACT FROM AUTHOR]

Background: Software requirements are features that a software system must have in order to meet the needs and solve a specific problem for which the software was developed. Objective: The purpose of this study is to identify the requirements and capabilities of a telemedicine system that is used to provide treatment plans for breast cancer patients. Material and Methods: This qualitative study was conducted with the participation of oncology specialists active in breast cancer treatment (n=12) and faculty members of health information management (n=4) and medical informatics (n=4). Data were collected through face-to-face interviews and analyzed using content analysis. Results: Functional requirements were one of the main themes, which were grouped into six main categories, including basic requirements for all users, requirements specific for system administrator, requirements specific for physicians involved in providing a treatment plan to patients, requirements specific for residents, requirements specific for patients, and communication with other information systems. Also, non-functional requirements were grouped into five main categories, including security and privacy, usability, reliability and supportability, integrity, and efficiency. Conclusion: Software requirements are a complex combination of the needs of different people at different levels of an organization and the environment in which the system must be implemented. During the requirements engineering process, the development team must interact with the stakeholders of the system in order to identify the exact and complete requirements of the software system. Therefore, stakeholders and end users of the system play an important role in identifying system requirements. [ABSTRACT FROM AUTHOR]

Background: Poor eating habits and unhealthy nutrition is a major risk factor for non-communicable diseases and a major threat to the current and future health of children and adolescents. Therefore, it seems necessary to use new and technology-based solutions in order to improve people's diet. Objective: Today, the use of digital technologies by nutritionists and their clients is increasing. In this regard, the purpose of this study is to investigate the roles and effectiveness of digital health-based interventions in diet and nutrition issues in children and adolescents. Material and Methods: In this narrative review study, the keywords "ehealth", "digital health", "mobile health", "Telemedicine", "Telehealth", "nutrition", "diet", "children" and "adolescent" in reputable databases including, PubMed, Web of Science, and Scopus to search and extract related literature with English language restrictions and no time limit. Results: The findings of the current research showed that various digital tools and technologies, including the Internet, computers, mobile apps, games, videos, social media, telemedicine, websites, and SMS text messaging have been used to develop practical digital interventions in the nutrition and diet field. The use of these technologies has led to an increase in awareness and self-monitoring, improvement of nutritional literacy, and change of attitude towards eating habits in children and their parents. Conclusion: Although there is considerable evidence on the effectiveness of using digital nutrition interventions, however, due to the heterogeneity in different studies, it is suggested that studies be conducted to investigate the effectiveness of using these interventions in the long term period. [ABSTRACT FROM AUTHOR]

Background: Today, the use of digital games has increased in healthcare, and speech disorders are no exception. To ensure the effectiveness of these games in clinical settings, they must be evaluated and their results determined. Objective: This study aimed to investigate the methods and results of using these games in speech therapy. Material and Methods: Four databases, including Medline (through PubMed), Scopus, Web of Science, and IEEE Xplore were searched to retrieved related articles published until July 14, 2021 by keywords and Mesh terms related to "Game" and "Speech". Articles were included in this systematic review that developed and evaluated a speech therapy game for children. Results: After examining the abstract and title of 1133 articles, finally, 24 studies were included in this systematic review. This systematic review showed that the games designed in this field had been evaluated from the following three aspects: 1) evaluating the performance of the speech recognition system used in these games, 2) assessing the usability of designed games, 3) evaluating the effectiveness of the designed game with end users. The results of these evaluations have shown that the games designed in this field can increase entertainment, desire to continue treatment, and motivation in children. Conclusion: The use of digital games in speech therapy has great potential to make therapy sessions fun for children, thus increasing compliance with the treatments provided. [ABSTRACT FROM AUTHOR]

Background: The most important factor in the survival of people in sudden cardiac arrest is the presence of a person trained to perform cardiopulmonary resuscitation (CPR) immediately after the occurrence of it. Virtual reality (VR) is a new technology that has been used for education in many medical fields. This technology has been proposed as a powerful tool for improving CPR performance. Objective: This systematic review aimed to investigate the effectiveness of using VR in CPR training. Material and Methods: Four databases, including Medline, Scopus, Web of Science, and IEEE Xplore were searched to retrieved related articles published until May 25, 2022. This systematic review was conducted based on Preferred Reporting Items for Systematic Reviews and Meta-Analyzes (PRISMA) guideline. All randomized trials that investigated the effects of VR on CPR education were included. Results: After reviewing the titles and abstracts of 3,348 retrieved studies, 42 studies seemed to be relevant, and after reviewing the full text of the articles, finally 10 articles were included in this systematic review. The oldest study was conducted in 2013 and the most recent one was conducted in 2022. The results of this research showed that virtual reality was as useful as face-to-face training in 100% of studies. The most positive effects of VR included improving knowledge retention, people's performance in terms of chest compressions, participants' satisfaction, ease of use, usefulness, appropriateness, and learning outcome. Conclusion: VR has great potential in increasing people's skills in CPR training and can be effective in this field. [ABSTRACT FROM AUTHOR]