1. A Technical Note: Inter-Observer and Inter-Modality Variability of Cone-Beam Computed Tomography (CBCT) and Ultrasound (US) in Stereotactic Body Radiotherapy for Kidney Cancer
- Author
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Hollis Luk, Matthew Wong, Wing-Ho Mui, Venus W Y Lee, Steven Cheung, Aray K. L. Wong, G Law, Frankle Lee, Francesca K. L. Ng, R Leung, and Dennis Y. K. Ngar
- Subjects
Cone beam computed tomography ,medicine.medical_specialty ,Modality (human–computer interaction) ,business.industry ,Ultrasound ,Observer (special relativity) ,medicine.disease ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Vertical direction ,Medicine ,Radiology ,business ,Nuclear medicine ,Fiducial marker ,Kidney cancer ,Stereotactic body radiotherapy - Abstract
Introduction: To investigate the inter-observer and inter-modality variabilities of two imaging guided equipments—cone-beam computed tomography (CBCT) and ultrasound (US) in kidney stereotactic body radiotherapy. Methods: A renal metastasis case implanted with three gold anchor fiducial markers was firstly scanned by US to acquire a 3-dimension US image and followed by 4-dimension CBCT in every fraction. Seven observers retrospectively registered the pre-treatment images with the corresponding reference images based on the gold markers. Registration uncertainty of the observers between two imaging modalities was evaluated. Results: The uncertainties over whole treatment course in CBCT were 0.88 mm, 1.94 mm and 0.86 mm in lateral, longitudinal and vertical directions respectively; while 0.8 mm, 0.97 mm and 1.36 mm were found in US. Conclusion: The greatest uncertainty was found in longitudinal direction in CBCT due to the fact that the respiration motion is the most rigorous in cranial-caudal direction. In US, since the probe was hold almost in upright position, the strong echo in vertical direction was attributed to the greatest uncertainty for such direction.
- Published
- 2017