1. End Stage Renal Disease in a Child with Epidermolysis Bullosa
- Author
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Marcela Valenzuela, María Joao Yubero, Felipe Cavagnaro, and Francis Palisson
- Subjects
Pathology ,medicine.medical_specialty ,medicine.diagnostic_test ,business.industry ,Urinary system ,medicine.medical_treatment ,030232 urology & nephrology ,urologic and male genital diseases ,medicine.disease ,Dermatology ,Tubulointerstitial Nephritis ,Connective tissue disease ,End stage renal disease ,030207 dermatology & venereal diseases ,03 medical and health sciences ,0302 clinical medicine ,medicine ,Renal biopsy ,Epidermolysis bullosa ,business ,Complication ,Dialysis - Abstract
Epidermolysis bullosa (EB) is an inherited connective tissue disease causing blisters in the skin and mucosal membranes. In severe cases, EB may be associated with renal damage through several mechanisms, mainly immunological ones. The present case described a young male with dystrophic recessive EB who developed an advanced chronic renal damage secondary to tubulointerstitial nephritis that was demonstrated by a renal biopsy. Unpublished previously, this complication should be considered among the possible causes of renal damage in EB. Also it is recommended a protocoled surveillance of renal and urinary tract complications in children with EB.
- Published
- 2016
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