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1. Dose-escalated radiotherapy with simultaneous integrated boost for bone metastases in selected patients with assumed favourable prognosis

Author

Potkrajcic Vlatko, Mueller Arndt-Christian, Frey Bettina, Gani Cihan, Zips Daniel, Hoffmann Ruediger, Frantz Sandra, Warm Verena, Paulsen Frank, and Eckert Franziska

Subjects
radiotherapy, oligometastatic disease, oligoprogressive disease, bone metastases, hypofractionated radiotherapy, simultaneous integrated boost, Medical physics. Medical radiology. Nuclear medicine, R895-920
Abstract

Stereotactic body radiotherapy (SBRT) concepts for dose escalation are increasingly used for bone metastases in patients with oligometastatic or oligoprogressive disease. For metastases that are not suitable for SBRT-regimens, a treatment with 30/40 Gy with simultaneous integrated boost (SIB) in 10 fractions represents a possible regimen. The aim of this study was to investigate the feasibility of this concept and the acute and subacute toxicities.

Published
2022
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