1. New Kid on the Block: A First Look at the Clinical Use of Pitolisant for Narcolepsy
- Author
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Christopher L. Drake, Kenneth Moss, Andrea Cuamatzi Castelan, Philip Cheng, Meeta Singh, Luisa Bazan, and Virginia Skiba
- Subjects
chemistry.chemical_compound ,Pitolisant ,chemistry ,business.industry ,Anesthesia ,Block (telecommunications) ,medicine ,Excessive daytime sleepiness ,General Medicine ,medicine.symptom ,medicine.disease ,business ,Narcolepsy - Abstract
Aims: Highlight pitolisant as an effective treatment for narcolepsy. Case Report: We describe two patients treated with pitolisant. Patient A showed decreased daytime sleepiness and improved social functioning. Patient B struggled to find a dose that kept side effects at a minimum. Discussion: This orphan drug has a unique mechanism of action, that combined with dosing flexibility allows for a treatment option that can better attend to individual differences in patient needs. Conclusion: The use of pitolisant presents some benefits and challenges, nonetheless offering a promising treatment for narcolepsy.
- Published
- 2021
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