1. Potential protective effects of red yeast rice in endothelial function against atherosclerotic cardiovascular disease.
- Author
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Feng SJ, Tang ZH, Wang Y, Tang XY, Li TH, Tang W, and Kuang ZM
- Subjects
- Apoptosis drug effects, Atherosclerosis pathology, Atherosclerosis physiopathology, Biological Products chemistry, Biological Products pharmacology, Cardiovascular Diseases pathology, Cardiovascular Diseases physiopathology, Cardiovascular Diseases prevention & control, Drugs, Chinese Herbal chemistry, Endothelium, Vascular cytology, Endothelium, Vascular physiology, Humans, Inflammation prevention & control, Lipid Metabolism drug effects, Oxidative Stress drug effects, Atherosclerosis prevention & control, Biological Products therapeutic use, Drugs, Chinese Herbal pharmacology, Drugs, Chinese Herbal therapeutic use, Endothelium, Vascular drug effects
- Abstract
Atherosclerotic cardiovascular disease (ASCVD) is the deadliest disease in the world, with endothelial injury occurring throughout the course of the disease. Therefore, improvement in endothelial function is of essential importance in the prevention of ASCVD. Red yeast rice (RYR), a healthy traditional Chinese food, has a lipid modulation function and also plays a vital role in the improvement of endothelial reactivity and cardiovascular protection; thus, it is significant in the prevention and treatment of ASCVD. This article reviews the molecular mechanisms of RYR and its related products in the improvement of endothelial function in terms of endothelial reactivity, anti-apoptosis of endothelial progenitor cells, oxidative stress alleviation and anti-inflammation., (Copyright © 2019 China Pharmaceutical University. Published by Elsevier B.V. All rights reserved.)
- Published
- 2019
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