1. Lateral medullary stroke in patient with granulomatous polyangiitis.
- Author
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Taraschenko OD, Amory CF, Waldman J, Hanspal EK, and Bernardini GL
- Subjects
- Acute Kidney Injury etiology, Adult, Anticoagulants therapeutic use, Biopsy, Brain Stem Infarctions diagnosis, Brain Stem Infarctions therapy, Diagnosis, Differential, Granulomatosis with Polyangiitis diagnosis, Granulomatosis with Polyangiitis therapy, Humans, Immunosuppressive Agents therapeutic use, Magnetic Resonance Imaging, Male, Plasmapheresis, Predictive Value of Tests, Renal Insufficiency etiology, Risk Factors, Treatment Outcome, Brain Stem Infarctions etiology, Granulomatosis with Polyangiitis complications
- Abstract
Granulomatous polyangiitis (GPA), also known as Wegener granulomatosis, is a systemic antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis that infrequently affects the central nervous system. We report a 41-year-old man with lateral medullary infarction who developed rapidly progressive renal failure. He was diagnosed with GPA based on positive serum c-ANCA and antiproteinase 3 antibodies and demonstration of pauci-immune crescentic glomerulonephritis on kidney biopsy. He was treated with Coumadin, pulse steroids, cyclophosphamide, and plasmapheresis. He had resolution of his neurologic deficits and improvement in renal function. This case report highlights the importance to consider GPA vasculitis in the differential diagnosis of stroke in patients with development of acute kidney injury., (Copyright © 2014 National Stroke Association. Published by Elsevier Inc. All rights reserved.)
- Published
- 2014
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