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WHO reported that there were 356,955,803 confirmed cases of COVID-19 and 5,610,291 deaths worldwide as of January 26, 2022 [1]. Meanwhile in Indonesia as of January 26, 2022, there were 4,301,193 positive cases of COVID- 19 and 144,254 deaths had been determined by the Ministry of Health of the Republic of Indonesia and the North Sulawesi Provincial Health Office reported 34,786 positive cases and 1,046 deaths [2]. During the COVID-19 pandemic, based on case reports, there were COVID-19 patients whose blood glucose levels increased while undergoing treatment at the hospital, even though these patients had no history of Diabetes mellitus. The effect of COVID-19 on increasing blood sugar levels is still not fully understood. Currently, while COVID-19 is still spreading, there is a need for continuous improvement in knowledge about the effective management of blood sugar control during COVID-19 infection. The purpose of this study was to investigate the relationship between blood glucose levels and clinical outcomes of COVID-19 patients undergoing treatment at the hospital. This research is a retrospective analysis using medical record data of Covid-19 patients treated at Sentra Medika Minahasa Utara Hospital for the period of March 2021 to August 2021. The results showed a significant relationship between elevated blood sugar levels and poor clinical outcomes in COVID-19 patients.

Sodium intake is very important in the mechanism of increasing blood pressure [1]. The effect of sodium intake in increasing blood pressure is through an increase in plasma volume (body fluid) and blood pressure [2]. The research was conducted in the form of an analytic survey with a cross-sectional study design. The data were processed using the SPSS program. The population is all students of SMAN 1 Amurang, South Minahasa District, the sample is taken by total sampling. From 67 samples, the minimum sodium content was 137 mEq/L and the maximum sodium content was 164. The average Na content was 143.54 mEq/L. The average systolic blood pressure was 119.04 mmHg and the average diastolic blood pressure was 79.70 mmHg. Based on the results of the Spearman correlation test, the correlation coefficient value (R = 0.069) with a significance of 0.579 for the correlation between sodium levels and systolic pressure. These results indicate that there is no statistically significant relationship between Na levels and systolic blood pressure. For the other Spearman correlation test results, the correlation coefficient value (R=-0.089) with a significance of 0.473 for the correlation between sodium levels and diastolic pressure. These results also show that there is no statistically significant relationship between sodium levels and diastolic blood pressure. It can be concluded that there is no relationship between serum sodium levels and blood pressure in adolescents in Amurang, South Minahasa District.