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INTRODUCTION: Tuberous sclerosis complex is an autosomal dominant, rare, multisystemic disease with variable presentation. Involvement of the renal, cardiac, nervous, and dermatological systems is possible, manifested in 90% of patients. The diagnosis is conducted through clinical criteria, and genetic tests may be requested. CASE REPORT: The reported case is of a 13-year-old female patient, diagnosed ten years ago with tuberous sclerosis, manifesting diffusely distributed hypochromic spots and nail lesions on hands and feet. In addition, the patient reports the recent onset of hyperchromic lesions on the face accompanied by itching and bruising. CONCLUSION: Early identification of tuberous sclerosis complex is necessary to minimize the multisystemic repercussions in the patient’s life. [ABSTRACT FROM AUTHOR]

Objective: To analyze student’s self-perception of the relation between factors linked to the academic environment and the development of anxious and depressive symptoms in the Medicine and Dentistry courses at the State University of Ponta Grossa. Methods: It is a cross-sectional and descriptive study, sociodemographic questionnaires and the Beck Depression and Anxiety Scale were applied. Data were analyzed using the Student’s T test, Mann-Whitney and the Pearson and Spearman test were used to determine correlations. Results: Findings show a significant number of students, especially females, manifest depressive and anxious symptoms. Findings also show students’ dissatisfaction with how the course impacts academic well-being was found. Conclusion: There is a need to rethink pedagogical methods and psychological support for students to minimize the negative impact of academic training on students’ mental health. [ABSTRACT FROM AUTHOR]