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The aim of this study was to evaluate the effects of active hexose correlated compound intake on the immune competence in healthy volunteers. Thirty-four subjects were randomized to receive placebo or active hexose correlated compound at 1.0 g/d for 4 weeks in early winter. Natural killer cell activity was significantly increased in both groups during the study period, the natural killer cell number, however, was not altered in the active hexose correlated compound group while placebo group showed remarkable decline. In addition, the score of immunological vigor, an index of total immune competence, was maintained in the active hexose correlated compound group although that of placebo group lowered during the test period. These results suggested that the continuous active hexose correlated compound intake maintained the immune competence against the seasonal change. [ABSTRACT FROM PUBLISHER]

Social life in Japan has been historically orientated towards hierarchical networks of social integration starting in the family home and extending to the neighborhood, company, and nation. In the postwar period, households and life courses were largely fixed, mediated by company society, a standard breadwinner family model and an ascent up an owner-occupied housing ladder. The bursting of the economic bubble two decades ago, and the subsequent 'lost decade', disrupted established flows into employment, family life, and owner-occupation. We examine recent restructuring of life courses around the home which has become characteristic of social changes and a medium of individualization. The home, once ingrained with notions of the eternal Japanese family, has become a conduit of atomization for younger generations who have experienced radical shifts in social and economic conditions. Since the 1990s numbers of single-only and couple-only households have ballooned while marriage and fertility rates have declined. Although homeownership norms have persisted, new patterns of renting and single living in the city, or remaining in the family home as a 'parasite single', are increasing. We consider how the reconstitution of 'home' under more insecure housing and employment conditions is embedded with the reshaping of life courses, housing pathways, and patterns of urban space and living. [ABSTRACT FROM AUTHOR]