1. Addressing Antimicrobial Resistance to Treat Children With Atopic Dermatitis in a Tertiary Pediatric Allergy Clinic.
- Author
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Bell, Matthew C., Stovall, Stephanie H., Scurlock, Amy M., Perry, Tamara T., Jones, Stacie M., and Harik, Nada S.
- Subjects
ANTIBIOTICS ,ATOPIC dermatitis ,CLINDAMYCIN ,DRUG resistance in microorganisms ,DRUG prescribing ,METHICILLIN ,MICROBIAL sensitivity tests ,STAPHYLOCOCCAL diseases ,PHYSICIAN practice patterns ,RETROSPECTIVE studies - Abstract
Background. Secondary skin infection with Staphylococcus aureus is a significant problem in atopic dermatitis (AD) patients. Objective. This study evaluated antimicrobial resistance patterns of S aureus isolates from skin lesions in AD patients and empiric antimicrobial prescribing patterns. Methods. Resistance patterns from positive skin cultures obtained from AD patients in the Allergy/Immunology clinic from May 1, 2006, to December 31, 2008, were compared with all outpatient wound cultures over the same period. Results. Fifty-nine cultures were obtained from 38 AD patients. S aureus was the most common pathogen cultured from AD patients (53/59 cultures). S aureus resistance to clindamycin and methicillin differed significantly between the study group and the outpatient reference population (37.7% vs 9.4% and 45.3% vs 76.4%). Clindamycin was the most commonly prescribed antimicrobial (59%). Overall, 31.4% of organisms showed resistance to the antimicrobial prescribed. Conclusions. Susceptibility profiles of S aureus isolates from AD patients vary significantly from that of the general population. [ABSTRACT FROM AUTHOR]
- Published
- 2012
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