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How do antidepressants work? This often-asked question continues to attract debate. The depressed individual features in many debates about antidepressants' action. With this focus, discussion oscillates over whether antidepressants work to remedy chemical imbalances in the brains of depressed people, or produce inauthentic states of being. This article argues shifting the analytic focus away from the depressed individual and onto the collective body, or assemblage, moves debates about how antidepressants work into more productive terrain. This provides a new way of looking at how antidepressants work to facilitate recovery from depression through a series of collaborative connections or relationships. Drawing on the charts, photos, and narratives from research encounters with people who take antidepressants, the article illustrates how medication facilitates the creation of active associations in an assemblage of forces. The article concludes by discussing the new ways of thinking about depression, medication and recovery suggested by this understanding of antidepressant action. [ABSTRACT FROM AUTHOR]

A key concern for qualitative inquiry is finding ways to account for nonhuman and emergent forms of life. Toward this, researchers are experimenting with research practices that decenter the human subject. Deleuze's (1977) assemblage concept has proved a useful resource for these methodological experiments. Most often, the assemblage concept has informed analysis and writing processes. This article puts the assemblage concept to work during each stage of an empirical research project exploring how people experience antidepressant use. It details seven ways that assemblages are used during concrete research processes across the span of the project. This strategy generates a sensibility toward qualitative inquiry described as orientating to assembling. The sensibility decenters the human as the focus of qualitative research. It enables the presence of nonhuman objects, not as acted-upon, but agents in the research processes. The article contributes to the challenges posed to human-centered qualitative research by reframing the focus entirely. It shows how using a sensibility that consistently decenters the human across all stages of empirical research projects, is a way that qualitative inquiry can account for more-than-human worlds. [ABSTRACT FROM AUTHOR]