1. Sporadic Burkitt’s lymphoma/acute B-cell leukaemia presenting with progressive proptosis and orbital mass in a child
- Author
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Carmela Borreggine, Luca Macarini, Nicola Delle Noci, Gianpaolo Grilli, Raffaela De Santis, Daniela Grasso, and Saverio Ladogana
- Subjects
Male ,Pathology ,medicine.medical_specialty ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Sporadic Burkitt's Lymphoma ,Biopsy ,Orbital mass ,medicine ,Exophthalmos ,Humans ,Pediatric Neuroradiology ,Radiology, Nuclear Medicine and imaging ,B cell ,Sinus (anatomy) ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,General Medicine ,medicine.disease ,Burkitt Lymphoma ,Magnetic Resonance Imaging ,Lymphoma ,medicine.anatomical_structure ,Child, Preschool ,030221 ophthalmology & optometry ,Orbital Neoplasms ,Neurology (clinical) ,business ,Burkitt's lymphoma - Abstract
Burkitt’s lymphoma (BL) is an aggressive B-cell non-Hodgkin lymphoma that is found predominantly in children, with the highest incidence occurring in Africa. The sporadic form occurs in non-endemic areas and typically involves the ileo-caecum and the bowel, whereas orbital and paranasal sinus involvement is rare. Here, we present an unusual case of sporadic BL in a Caucasian male child with rapidly progressive painful proptosis of the right eye. Magnetic resonance imaging showed an oval-shaped, extraconal mass in the supero-lateral part of the right orbit that deformed and dislocated the eyeball antero-inferiorly. The patient underwent anterior orbitotomy, and a biopsy of the excised tissue revealed a starry-sky appearance characteristic of BL. Postoperative aggressive chemotherapy was initiated with a good response after one week.
- Published
- 2016