11 results on '"Pfeffer G"'
Search Results
2. Letter Regarding: Subtalar Arthrodesis Union Rates With and Without Adjacent Ankle Arthrodesis.
- Author
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Pattisapu N, Michalski M, and Pfeffer G
- Subjects
- Humans, Joints, Arthrodesis, Ankle Joint surgery, Retrospective Studies, Treatment Outcome, Ankle, Subtalar Joint surgery
- Published
- 2023
- Full Text
- View/download PDF
3. Cavovarus With a Twist: Midfoot Coronal and Axial Plane Rotational Deformity in Charcot-Marie-Tooth Disease.
- Author
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An T, Haupt E, Michalski M, Salo J, and Pfeffer G
- Subjects
- Adult, Case-Control Studies, Foot, Humans, Retrospective Studies, Weight-Bearing, Charcot-Marie-Tooth Disease diagnostic imaging, Charcot-Marie-Tooth Disease surgery
- Abstract
Background: The cavovarus deformity of Charcot-Marie-Tooth (CMT) disease is often characterized by a paradoxical relationship of hindfoot varus and forefoot valgus. The configuration of the midfoot, which links these deformities, is poorly understood. Accurate assessment of 3-dimensional alignment under physiologic loadbearing conditions is possible using weightbearing computed tomography (WBCT). This is the first study to examine the rotational deformity in the midfoot of CMT patients and, thus, provide key insights to successful correction of CMT cavovarus foot., Methods: A total of 27 WBCT scans from 21 CMT patients were compared to control WBCTs from 20 healthy unmatched adults. CMT patients with a history of bony surgery, severe degenerative joint disease, or open physes in the foot were excluded. Scans were analyzed using 3-dimensional software. Anatomic alignment of the tarsal bones was calculated relative to the anterior-posterior axis of the tibial plafond in the axial plane, and weightbearing surface in the coronal plane., Results: Maximal rotational deformity in CMT patients occurred at the transverse tarsal joints, averaging 61 degrees of external rotation (supination), compared to 34 degrees among controls ( P < .01). The talonavicular joint was also the site of peak adduction deformity in the midfoot, with an average talonavicular coverage angle measuring 12 degrees compared with -11 degrees in controls ( P < .01)., Conclusion: This 3-dimensional WBCT analysis is the first to isolate and quantify the multiplanar rotational deformity in the midfoot of CMT patients. Compared with healthy unmatched control cases, CMT patients demonstrated increased axial plane adduction and coronal plane rotation at the talonavicular (TN) joint. These findings support performing soft tissue release at the TN joint to abduct and derotate the midfoot as a first step for targeted deformity correction., Level of Evidence: Level III, retrospective case-control study.
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- 2022
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4. Safety and Efficacy of Postoperative Indwelling Popliteal Nerve Catheters for Outpatient Charcot-Marie-Tooth Surgery.
- Author
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An T, Schwartz E, Kissen M, Pollock G, and Pfeffer G
- Subjects
- Adolescent, Adult, Catheters, Indwelling, Humans, Middle Aged, Outpatients, Oxycodone therapeutic use, Pain Measurement, Pain, Postoperative prevention & control, Prospective Studies, Young Adult, Analgesics, Opioid, Charcot-Marie-Tooth Disease complications, Charcot-Marie-Tooth Disease surgery
- Abstract
Background: Outpatient surgical deformity correction for Charcot-Marie-Tooth (CMT) disease is limited by effective postoperative pain control. Our previous institutional protocol for foot and ankle surgery in this population included preoperative single-injection nerve blocks, but patients often experienced uncontrolled pain when the block wore off postoperative day 0 or 1, resulting in high opioid requirements and unplanned emergency department visits. The use of ultrasonography-guided continuous nerve catheters in CMT patients has not previously been studied. We aimed to prospectively investigate the safety and efficacy of ultrasonography-guided indwelling popliteal catheters in CMT patients undergoing outpatient foot deformity correction surgery., Methods: Twenty CMT patients, average 28 (range 13-53) years old, undergoing reconstructive surgery by a single foot and ankle attending surgeon were consented for preoperative ultrasonography-guided popliteal catheters. This series included 24 total outpatient procedures; 4 were staged bilateral. Indwelling popliteal catheters were maintained on discharge, providing continuous infusion until postoperative day (POD) 3, and then self-discontinued. Patients were prescribed oxycodone 5 mg (60-80 pills) as needed for breakthrough pain. Outcomes collected included daily pain scores (0-10), an opioid pill count on POD 14, and patient satisfaction ratings. Neurologic evaluation by 5-point 10g Semmes-Weinstein monofilament testing was performed preoperatively and on POD 14., Results: There were no observed catheter-site infections or hematomas. Nine of the patients had pre-existing sensory deficits involving at least 2 areas on the 5-point monofilament test. Postoperative testing showed these deficits were unchanged and there were no instances of new sensory deficits. Postoperative pain scores were typically low, with median values (interquartile ranges [IQRs]) of 3.5 (2.0-5.0) on POD 1, 2.5 (2.0-5.0) on POD 2, and 2.5 (1.0-3.75) on POD 3. At POD 14, pain was 1.0 (0-1.0). Patients consumed a median of 25 oxycodone pills (IQR 8-43) over 2 weeks, less than half the prescribed number. Patient satisfaction was high. All patients reported they would choose to have a nerve catheter again for a similar surgery., Conclusion: This cases series demonstrated that regional anesthesia using ultrasonography-guided indwelling popliteal catheters was safe and effective for pain control in CMT patients undergoing outpatient foot and ankle surgery. Opioid consumption was comparable to published rates following major bony procedures, and no patients required emergent treatment or hospital admission for uncontrolled pain. No new sensory deficits were detected and patients with underlying sensory deficits remained unchanged. Patients were highly satisfied., Level of Evidence: Level IV, case series.
- Published
- 2022
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- View/download PDF
5. Abnormal Bone Morphology in Charcot-Marie-Tooth Disease.
- Author
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Michalski MP, An TW, Haupt ET, Yeshoua B, Salo J, and Pfeffer G
- Subjects
- Humans, Osteotomy methods, Weight-Bearing, Calcaneus diagnostic imaging, Calcaneus surgery, Charcot-Marie-Tooth Disease surgery, Talus surgery
- Abstract
Background: Although long suspected, it has yet to be shown whether the foot and ankle deformities of Charcot-Marie-Tooth disease (CMT) are generally associated with abnormalities in osseous shape. Computed tomography (CT) was used to quantify morphologic differences of the calcaneus, talus, and navicular in CMT compared with healthy controls., Methods: Weightbearing CT scans of 21 patients (27 feet) with CMT were compared to those of 20 healthy controls. Calcaneal measurements included radius of curvature, sagittal posterior tuberosity-posterior facet angle, and tuberosity coronal rotation. Talar measurements included axial and sagittal body-neck declination angle, and coronal talar head rotation. Surface-mesh model analysis of the hindfoot was performed comparing the average of the CMT cohort to the controls using a CT analysis software (Disior Bonelogic 2.0). Means were compared with a t test ( P < .05)., Results: CMT patients had significantly less talar sagittal declination vs controls (17.8 vs 25.1 degrees; P < .05). Similarly, CMT patients had less talar head coronal rotation vs controls (30.8 vs 42.5 degrees; P < .001). The calcaneal radius of curvature in CMT patients was significantly smaller than controls (822.8 vs 2143.5 mm; P < .05). CMT sagittal posterior tuberosity-posterior facet angle was also significantly different from that of controls (60.3 vs 67.9 degrees respectively; P < .001).Surface-mesh model analysis demonstrated the largest differences in morphology at the navicular tuberosity, medial talar head, sustentaculum tali, and anterior process of the calcaneus., Conclusion: This is the first study to quantify the morphologic differences in hindfoot osteology seen in CMT patients. Patients identified with osseous changes of the calcaneus, especially a smaller axial radius of curvature, may benefit from a 3-dimensional osteotomy for correction.
- Published
- 2022
- Full Text
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6. Dexamethasone Addition to Popliteal Nerve Blocks: Effects on Duration of Analgesia and Incidence of Postoperative Nerve Complication.
- Author
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Noori N, Anand K, Pfeffer G, and Thordarson D
- Subjects
- Adult, Aged, Double-Blind Method, Female, Humans, Incidence, Intraoperative Care, Male, Middle Aged, Orthopedic Procedures, Pain Management adverse effects, Pilot Projects, Prospective Studies, Time Factors, Adjuvants, Anesthesia administration & dosage, Analgesia methods, Ankle surgery, Dexamethasone administration & dosage, Duration of Therapy, Foot surgery, Nerve Block methods, Pain Management methods, Pain, Postoperative prevention & control, Postoperative Complications epidemiology, Postoperative Complications etiology, Tibial Neuropathy epidemiology, Tibial Neuropathy etiology
- Abstract
Background . The purpose of this prospective, double-blinded randomized control pilot study was to evaluate the effect of adjunctive dexamethasone on analgesia duration and the incidence of postoperative neuropathic complication. Peripheral nerve blocks are an effective adjunct to decrease postoperative pain in foot and ankle surgery, and any possible modalities to augment their efficacy is of clinical utility. Methods . Patients were randomly assigned to a control group (n = 25) receiving nerve blocks of bupivacaine and epinephrine or an experimental group (n = 24) with an adjunctive 8 mg dexamethasone. The patients, surgeons, and anesthesiologists were all blinded to allocation. Patients had a minimum 1 year postoperative follow-up. Results . Forty-nine patients completed the protocol. There was no statistically significant difference in analgesia duration ( P = .38) or postoperative neuropathic complication incidence ( P = .67) between the 2 groups. Conclusions . The addition of dexamethasone to popliteal nerve blocks does not appear to affect analgesia duration or incidence of postoperative neuropathic complications. However, our study was underpowered, and we recommend a larger scale prospective study for validation. Levels of Evidence: Level II: Prospective, randomized control pilot study.
- Published
- 2021
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- View/download PDF
7. Superiority Versus Noninferiority.
- Author
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Pfeffer G, Pinzur MS, and Adams W
- Subjects
- Humans, United States, United States Food and Drug Administration, Drug Development, Equivalence Trials as Topic, Evidence-Based Medicine, Research Design
- Published
- 2020
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8. Comparison of Lateralizing Calcaneal Osteotomies for Varus Hindfoot Correction.
- Author
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An TW, Michalski M, Jansson K, and Pfeffer G
- Subjects
- Humans, Models, Anatomic, Printing, Three-Dimensional, Calcaneus diagnostic imaging, Calcaneus surgery, Charcot-Marie-Tooth Disease diagnostic imaging, Charcot-Marie-Tooth Disease surgery, Osteotomy methods, Tomography, X-Ray Computed methods
- Abstract
Background: There is limited consensus on the optimal operative technique for correcting heel varus in patients with Charcot-Marie-Tooth (CMT) disease. This comparative study evaluated the ability of 4 lateralizing calcaneal osteotomies, with and without Dwyer wedge resection and coronal rotation of the posterior tuberosity, to correct severe heel varus., Methods: The computed tomography (CT) scan of a teenage CMT patient with severe hindfoot varus was used to create 3-dimensional (3D)-printed models of the talus, calcaneus, and cuboid. A custom jig facilitated precise replication of the osteotomy cuts. Four different configurations were created: oblique osteotomy with lateralization, oblique osteotomy with lateralization and internal rotation of the posterior tuberosity, Dwyer wedge resection with lateralization, and Dwyer wedge resection with lateralization and internal rotation. CT scans were performed on each model before and after osteotomy. Statistical analysis was used to evaluate differences in several predefined radiographic parameters., Results: The sequential transformations generated increasing lateral translation of the weight-bearing calcaneus. Dwyer wedge osteotomy significantly improved lateralization (effect = 8.0 mm), valgus hindfoot angle (effect = 6.1 degrees), and coronal calcaneal tilt (effect = -17.6 degrees) compared with the oblique osteotomy. Internal rotation of the posterior tuberosity further improved lateralization (effect = 3.3 mm), valgus hindfoot angle (effect = 2.5 degrees), and coronal calcaneal tilt (effect = -11.7 degrees). Dwyer osteotomy models had on average 5-mm shorter posterior tuberosity lengths than the oblique osteotomies. The addition of rotation did not significantly affect length., Conclusions: Significant lateralization of the posterior tuberosity was achieved in all transformations. The Dwyer wedge osteotomy improved hindfoot valgus angle, coronal calcaneal tilt, and lateralization of the weight-bearing surface compared with oblique osteotomy. Posterior tuberosity internal rotation further lateralized the plantar surface and normalized weight bearing. Lateralization, combined with Dwyer osteotomy and coronal plane internal rotation, achieved the greatest correction of varus heel., Clinical Relevance: This study compares multiple lateralizing calcaneal osteotomies and proposes a combined technique of lateralization, Dwyer wedge resection, and coronal plane rotation to address advanced cavovarus hindfoot deformities.
- Published
- 2018
- Full Text
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9. Achilles Pullout Strength After Open Calcaneoplasty for Haglund's Syndrome.
- Author
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Pfeffer G, Gonzalez T, Zapf M, Nelson TJ, and Metzger MF
- Subjects
- Biomechanical Phenomena, Bone Density, Cadaver, Calcaneus diagnostic imaging, Calcaneus pathology, Female, Humans, Male, Radiography, Syndrome, Achilles Tendon physiology, Calcaneus surgery, Orthopedic Procedures rehabilitation
- Abstract
Background: Haglund's syndrome involves a prominent posterior superior prominence of the calcaneus. If nonoperative management fails, operative management with calcaneoplasty is often needed. No study has assessed Achilles tendon pullout strength after an open calcaneoplasty for Haglund's syndrome. The purpose of this study was to investigate those changes in a cadaveric model and provide objective data upon which to base postoperative recovery., Methods: Seven matched pairs of cadaveric specimens (mid-tibia to toes) were divided into 2 cohorts: (1) intact/untreated and (2) open resection. The open resection group was treated with an open calcaneoplasty through a posterior approach using a microsagittal saw. We compared Achilles pullout strength between the 2 groups through the use of a mechanical testing system. Specimens were then loaded to failure. Lateral radiographs were obtained before and after surgery to quantify bone removal. Outcome measures included height of bony resection, angle of bone resection, and load to failure., Results: The mean maximum pullout strength was significantly higher in the intact specimens (1300 ± 500 N) compared to the open resection group (740 ± 180 N) ( P < .01), representing a 45% reduction in pullout force in the open resection group. Pullout force was significantly correlated to bone mineral density (BMD) ( P < .05). Pullout force was negatively correlated to both radiographic measures of resection level, angle, and height, but neither of these were significant., Conclusion: Open calcaneoplasty demonstrated a significant weakness of the Achilles tendon insertion. Pullout strength of the Achilles was also positively correlated with BMD., Clinical Relevance: Biomechanical evidence presented above supports the practice of protected weightbearing and cautious return to activity after open calcaneoplasty for Haglund's syndrome.
- Published
- 2018
- Full Text
- View/download PDF
10. Comparison of custom and prefabricated orthoses in the initial treatment of proximal plantar fasciitis.
- Author
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Pfeffer G, Bacchetti P, Deland J, Lewis A, Anderson R, Davis W, Alvarez R, Brodsky J, Cooper P, Frey C, Herrick R, Myerson M, Sammarco J, Janecki C, Ross S, Bowman M, and Smith R
- Subjects
- Adult, Aged, Aged, 80 and over, Fasciitis physiopathology, Female, Foot Diseases physiopathology, Heel, Humans, Male, Middle Aged, Pain etiology, Pain Management, Physical Therapy Modalities, Prospective Studies, Treatment Outcome, Fasciitis therapy, Foot Diseases therapy, Orthotic Devices standards
- Abstract
Fifteen centers for orthopaedic treatment of the foot and ankle participated in a prospective randomized trial to compare several nonoperative treatments for proximal plantar fasciitis (heel pain syndrome). Included were 236 patients (160 women and 76 men) who were 16 years of age or older. Most reported duration of symptoms of 6 months or less. Patients with systemic disease, significant musculoskeletal complaints, sciatica, or local nerve entrapment were excluded. We randomized patients prospectively into five different treatment groups. All groups performed Achilles tendon- and plantar fascia-stretching in a similar manner. One group was treated with stretching only. The other four groups stretched and used one of four different shoe inserts, including a silicone heel pad, a felt pad, a rubber heel cup, or a custom-made polypropylene orthotic device. Patients were reevaluated after 8 weeks of treatment. The percentages improved in each group were: (1) silicone insert, 95%; (2) rubber insert, 88%; (3) felt insert, 81%; (4)stretching only, 72%; and (5) custom orthosis, 68%. Combining all the patients who used a prefabricated insert, we found that their improvement rates were higher than those assigned to stretching only (P = 0.022) and those who stretched and used a custom orthosis (P = 0.0074). We conclude that, when used in conjunction with a stretching program, a prefabricated shoe insert is more likely to produce improvement in symptoms as part of the initial treatment of proximal plantar fasciitis than a custom polypropylene orthotic device.
- Published
- 1999
- Full Text
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11. Chronic disorders of the Achilles tendon: results of conservative and surgical treatments.
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Johnston E, Scranton P Jr, and Pfeffer GB
- Subjects
- Adult, Chronic Disease, Female, Humans, Male, Middle Aged, Retrospective Studies, Sex Factors, Tenosynovitis pathology, Tenosynovitis surgery, Treatment Outcome, Achilles Tendon pathology, Achilles Tendon surgery, Tenosynovitis therapy
- Abstract
We reviewed our results of nonoperative and operative treatment of chronic Achilles tenosynovitis to further define outcomes and treatment parameters. Forty-one patients presented with an average of 14 weeks of Achilles tendon symptoms. All patients received nonsurgical treatment initially, and 21 patients (51%) recovered after an average of 18 weeks of therapy. Three additional patients improved after brisement of the tendon/peritenon interspace. Seventeen of 41 patients eventually underwent soft tissue tenolysis and/or excision of degenerative tendon cysts. Those patients who responded to nonoperative therapy tended to be younger (average age, 33 years) than those who had degenerative tendon changes requiring surgery (average age, 48 years). All surgical patients were able to return to unrestricted activity after 31 weeks (range, 27-48 weeks). We believe 4 to 6 months of nonsurgical therapy is appropriate for middle aged patients or athletes with chronic Achilles tenosynovitis. Those that fail this treatment will improve with a limited debridement of diseased tissue without excessive soft tissue dissection of the tendon.
- Published
- 1997
- Full Text
- View/download PDF
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