1. Quantitative Techniques in Neuropathology
- Author
-
Ian McMillan, George J. Losos, Brian R. Broxup, and George Yipchuck
- Subjects
Male ,0301 basic medicine ,Computer science ,Statistics as Topic ,Rats, Inbred Strains ,02 engineering and technology ,Cell Biology ,Neuropathology ,021001 nanoscience & nanotechnology ,Toxicology ,Tissue Preparation ,Rats ,Pathology and Forensic Medicine ,03 medical and health sciences ,Nerve Fibers ,030104 developmental biology ,Neurology ,Sural Nerve ,Pathology ,Animals ,Biochemical engineering ,0210 nano-technology ,Molecular Biology ,Computer technology - Abstract
In the future, quantitative techniques will probably be used in industry as part of Tier II studies for the evaluation of chemicals and drugs for their neurotoxic potential. Movement towards quantifying some structures or neuropathological changes will be made possible by advances in tissue preparation and computer technology. Emphasis will need to be placed on standardized techniques, good quality samples and sampling techniques in order to produce good quantitative data in a reasonable time. In this paper, different sampling techniques are evaluated using a cross section of rat sural nerve as the tissue for quantitative investigation.
- Published
- 1990