1. Association Between Severity of COVID-19 Respiratory Disease and Risk of Obstructive Sleep Apnea.
- Author
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Iannella G, Vicini C, Lechien JR, Ravaglia C, Poletti V, di Cesare S, Amicarelli E, Gardelli L, Grosso C, Patacca A, Magistrelli E, De Benedetto M, Toraldo DM, Arigliani M, Cammaroto G, Meccariello G, De Vito A, Magliulo G, Greco A, de Vincentiis M, Ralli M, Pace A, Montincone V, Maniaci A, Cocuzza S, Seligardi M, di Giacinto I, and Corso RM
- Subjects
- Humans, Retrospective Studies, Polysomnography methods, Risk Factors, Surveys and Questionnaires, COVID-19 complications, COVID-19 epidemiology, Sleep Apnea, Obstructive complications, Sleep Apnea, Obstructive epidemiology
- Abstract
Objectives: The purpose of this observational retrospective study was to evaluate, in patients with a severe acute respiratory syndrome coronavirus 2 infection, the association between the severity of coronavirus disease 2019 (COVID-19) respiratory illness and the risk of infected patients to develop obstructive sleep apnea (OSA)., Methods: Ninety-six patients with confirmed COVID-19 infection were enrolled in the study. The STOP-BANG questionnaire to investigate the risk of the OSA syndrome was filled in by the patients at admission. The enrolled patients were divided into 2 groups according to the respiratory disease: group 1 (72 patients), hospitalized patients undergoing conventional oxygen therapy; group 2 (24 patients), patients requiring enhanced respiratory support. STOP-BANG results of these 2 groups were compared to observe whether patients with high OSA risk more frequently presented a severe form of COVID-19., Results: 41.6% of the patients in group 2 had a STOP-BANG score between 5 and 8 (high risk of having apnea); in contrast, 20.8% of the patients in group 1 had a STOP-BANG score between 5 and 8, with a statistically significant difference between the 2 groups ( P = .05). A complementary trend was observed regarding the proportion of patients in the range 0 to 2, which classifies patients at a low risk of OSA (48.6% vs 20.8% for groups 1 and 2, P = .01)., Conclusions: According to our data, the chances of having a severe case of COVID-19 should be considered in patients at high risk of OSA., Current Knowledge/study Rationale: Emerging research suggests that OSA could represent a potentially important risk factor for the severe forms of COVID-19. The purpose of this observational retrospective study was to evaluate the potential association between OSA and the severity of COVID-19 disease., Study Impact: According to our data, the likelihood of contracting a severe form of COVID-19 disease should be considered in patients at high risk of OSA., Competing Interests: Declaration of Conflicting InterestsThe author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
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