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Esophageal surgery comprises a variety of procedures of differing complexity to treat functional and structural disorders of the esophagus. Local disease extension, surgical repair technique, and physical status of the patient primarily dictate anesthetic management of patients with esophageal pathology. Because the esophagus is in close proximity to vital organs and structures, a specific knowledge of the anatomy is essential to realize how esophageal pathology can compromise elemental physiological functions. A com prehensive anesthetic plan requires a detailed under standing of the surgical procedure in terms of approach, the extent of the operation, and associated complica tions. Consideration of comorbid conditions is equally important, as esophageal surgery is frequently per formed in debilitated and polytraumatized patients. The following article will review clinical manifestation, surgi cal therapy, and perioperative anesthetic management of the most commonly encountered esophageal disor ders. Specifically, anesthetic considerations in gastro esophageal reflux disease, esophageal carcinoma, esophageal perforation, and a variety of other esopha geal disorders will be discussed.