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A case of testicular specialized gonadal stroma tumor was evaluated by histologic, ultrastructural and immunohistochemical techniques in a young adult male patient. The neoplastic cells were organized in cords or tubular structures delimited by a basement membrane. The ultrastructural findings suggested a diagnosis of a partially differentiated Sertoli cell tumor. This was also supported by the presence of a vimentin rich cytoskeleton, which is normally present in Sertoli and Leydig cells. The tumor cells did not secrete steroid hormones, as suggested by clinical findings, as well as by hormonal, immunohistochemical, and ultrastructural observations.

Two cases of lipoma of the tuber cinereum, unexpectedly discovered in the course of autopsy examination, are reported. Each case was thoroughly investigated by serial sectioning of both the diencephalic floor and the tumor. Some peculiar findings observed and a complete survey of the literature revealed that such a growth may be considered an incomplete benign mesenchymoma, i.e., a mixed tumor of mesenchymal derivates, according to Stout (14). The error in development, consisting in the inclusion of embryonal germs of primitive meninx into the nervous system, may occur early during the third month of intrauterine life, at the time of the formation of the primitive septa.