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14 results on '"W Bernhard"'

1. Effect of Beta-Mimetic Drugs on Phospholipid Synthesis in the Isolated Lung

Author

P. von Wichert, W. Bernhard, and Bernd Müller

Subjects
chemistry.chemical_compound, Lung, medicine.anatomical_structure, Pulmonary surfactant, chemistry, Biochemistry, Biosynthesis, Phospholipid, medicine, Respiratory system, Biology, Beta (finance), Phospholipid synthesis
Published
2015

4. Early versus Delayed Selective Surfactant Treatment for Neonatal Respiratory Distress Syndrome

Author

Chao Chen, Julia Gunkel, W. Bernhard, Anne Lotthé, Hélène Marchandin, Hristo Stanchev, Selma W. Lavrijsen, Jian Wang, Gitte Esberg, Ann Hellström, Concepción González Fuentes, Lars Bender, María Luisa Domínguez Quintero, Druck Reinhardt Druck Basel, Irena Ulanovsky, Olli Pitkänen, Yinghui Zhang, Pernille Pedersen, Fabienne Poree, Hong Zhu, Manon J.N.L. Benders, Wengqing Kang, Ingrid C. van Haastert, Chatarina Löfqvist, Yasmin Anton, Roger F. Soll, Floris Groenendaal, Chongchen Zhou, Laura Martelius, Hong Xiong, Manon J. Benders, Sylvie Parer, Jian Pan, Christian Eschen, Jie Yan, Anne Monique Nuyt, Qing Wang, Imad R. Makhoul, Finn Ebbesen, Orna Mick, María Teresa Ferrer Castillo, Emilie Jourdes, Jes Reinholdt, Alain Beuchée, Tatiana Smolkin, Péter Temesvári, Ferenc Domoki, Yanhong Li, Zhihui Xiao, Huiqing Sun, Sture Andersson, Andreas Kreft, Aksel Bertelsen, C. Maas, Ferenc Bari, Mark J. Gotink, Wissal Ben Jmaa, C. Wiechers, Arno van Heijst, Satz Mengensatzproduktion, Xavier Navarro, C.F. Poets, Xiuyong Cheng, Amerik C. de Mol, Anne Filleron, Jesper Fenger-Grøn, Tiphaine Mialet-Marty, Cecilia Janér, Otto Helve, A.R. Franz, Malgorzata A. Verboon-Maciolek, Belén Jiménez Crespo, Eric Jeziorski, Majd I. Makhoul, Jørn Kroner, Shraga Blazer, Henrik Verder, Marie Josefine Høvring, Olivier Prodhomme, Xing Feng, Marianne Dahl, Eduardo García Soblechero, Orsolya Oláh, Fredrik Lundberg, Xueming Zhu, Kirsi Lauerma, Peter H. Dijk, Karina J. Kersbergen, Bernhard Resch, Linda S. de Vries, Xiaozhong Li, Tine Brink Henriksen, Nga N'Guyen, Britt J. van Kooij, Bengt Andreasson, Changlian Zhu, Gilles Cambonie, Marie-Noëlle Didelot, Jing Guo, Liina Süvari, Valéria Tóth-Szűki, Kian D. Liem, Lars J. Björklund, Rob Rodrigues Pereira, Joppe Nijman, Patrick Pladys, and Christian V. Hulzebos

Subjects
Neonatal respiratory distress syndrome, Pulmonary surfactant, business.industry, Anesthesia, Pediatrics, Perinatology and Child Health, Medicine, business, medicine.disease, Developmental Biology
Published
2013

5. Elective High-Frequency Oscillatory Ventilation versus Conventional Ventilation for Acute Pulmonary Dysfunction in Preterm Infants

Author

Druck Reinhardt Druck Basel, Morten Breindahl, Hyun Ju Lee, Mari Jeeva Sankar, Peter Husslein, Mireille Vanpée, Vinod K. Paul, S. Mitt, Marta Thio Lluch, Mats Blennow, Ee-Kyung Kim, Ivo Bendix, Frank van Bel, Roger F. Soll, Linda S. de Vries, Gabriela Zaharie, Ruben Bromiker, Lasse Dührsen, Sung-Il Cho, Yechiel Schlesinger, Jin A. Lee, Jean-Claude Fauchère, Han Suk Kim, Marco Sifringer, A.R. Franz, Rene M. H. Wijnen, Gurudayal Singh Toteja, Jeroen Hendrikse, Michael P. Sherman, Munnalal Jaipal, Gorm Greisen, Michael J. Kaplan, Kees P. van de Ven, Neil Marlow, Floris Groenendaal, Charles Christoph Roehr, C.F. Poets, Shuchita Gupta, Anand Agarwal, Mark Dzietko, Monika Olischar, Kyeung-Yeup Lee, Jung-Hwan Choi, Netanela Ernest, Mark A. Underwood, Steven J. McElroy, Dick Tibboel, Harm A.W.M. Tiddens, David C. Kasper, Michael Hayde, Satz Mengensatzproduktion, Hanneke IJsselstijn, Kerstin Genz, W. Bernhard, Marjolein Spoel, Ursula Felderhoff-Mueser, Andrea-Romana Prusa, Eduardo Vilamor, Jean-Charles Picaud, Sunita Bhatia, Heui Seung Jo, A. Full, Daniele De Luca, Wim C. J. Hop, Veena Devgan, Manon J.N.L. Benders, Chang Won Choi, J. Arand, Vinzenz Boos, Deenanath Virmani, Sinno H.P. Simons, Beyong Il Kim, Arnold Pollak, Ashok K. Deorari, C. Maas, Cathy Hammerman, Yoon Hwan Chang, Ramesh Agarwal, Michael S. Schimmel, and Maskit Bar Meir

Subjects
Lung Diseases, Respiratory Distress Syndrome, Newborn, business.industry, Infant, Newborn, High-Frequency Ventilation, Infant, Premature, Diseases, Lung Injury, Pulmonary Dysfunction, Respiration, Artificial, Anesthesia, Chronic Disease, Pediatrics, Perinatology and Child Health, Humans, Medicine, business, Infant, Premature, Developmental Biology, High frequency oscillatory ventilation, Conventional ventilation
Abstract

Respiratory failure due to lung immaturity is a major cause of mortality in preterm infants. Although the use of intermittent positive pressure ventilation in neonates with respiratory failure saves lives, its use is associated with lung injury and chronic lung disease (CLD). A newer form of ventilation called high-frequency oscillatory ventilation (HFOV) has been shown to result in less lung injury in experimental studies.The objective of this review is to determine the effect of the elective use of HFOV as compared to conventional ventilation (CV) on the incidence of CLD, mortality and other complications associated with prematurity and assisted ventilation in preterm infants who are mechanically ventilated for respiratory distress syndrome (RDS).Searches were made of the Oxford Database of Perinatal Trials, MEDLINE, EMBASE, previous reviews including cross-references, abstracts, conferences and symposia proceedings, expert informants, journal hand searching by the Cochrane Collaboration, mainly in the English language. The search was updated in January 2009.Randomized controlled trials comparing HFOV and CV in preterm or low birth weight infants with pulmonary dysfunction, mainly due to RDS, who required assisted ventilation. Randomization and commencement of treatment needed to be as soon as possible after the start of CV and usually in the first 12 h of life.The methodological quality of each trial was independently reviewed by the various authors. The standard effect measures are relative risk (RR) and risk difference (RD). From 1/RD the number needed to treat to produce one outcome were calculated. For all measures of effect, 95% confidence intervals were used. In subgroup analyses the 99% CIs are also given for summary RRs in the text. Meta-analysis was performed using a fixed effect model. Where heterogeneity was over 50%, the random effects RR is also given.Seventeen eligible studies of 3,652 infants were included. Meta-analysis comparing HFOV with CV revealed no evidence of effect on mortality at 28-30 days of age or at approximately term equivalent age. These results were consistent across studies and in subgroup analyses. The effect of HFOV on CLD in survivors at term equivalent gestational age was inconsistent across studies and the reduction was of borderline significance overall. The effect was similar in trials with a high lung volume strategy for HFOV targeting at very low FiO(2) and trials with a high lung volume strategy with somewhat higher or unspecified target FiO(2). Subgroups of trials showed a significant reduction in CLD with HFOV when no surfactant was used, when piston oscillators were used for HFOV, when lung protective strategies for CV were not used, when randomization occurred at two to six hours of age, and when inspiratory:expiratory ratio of 1:2 was used for HFOV. In the meta-analysis of all trials, pulmonary air leaks occurred more frequently in the HFOV group. In some studies, short-term neurological morbidity with HFOV was found, but this effect was not statistically significant overall. The subgroup of two trials not using a high-volume strategy with HFOV found increased rates of grade 3 or 4 intraventricular hemorrhage and of periventricular leukomalacia. An adverse effect of HFOV on long-term neurodevelopment was found in one large trial but not in the five other trials that reported this outcome. The rate of retinopathy of prematurity is reduced overall in the HFOV group.

Published
2013

6. Referate – Abstracts – Analyses

Author

P.O. Rudert, H. Braunsteiner, W. Bernhard, Miriam Reiner, C.G. Bergstrand, George Discombe, Vaclovas Darguzas, N. Kurnick, Febvre Hl, B. Vahlquist, I. Snapper, B. Schneid, Adolf Staffe, F. Thedering, Kurt G. Stern, and Richard L. Fenichel

Subjects
Hematology, General Medicine
Published
1950

8. Contents, Vol. 14, 1964

Author

P. Adler, Hubert C. Soltan, W. Bernhard, Mary Whittaker, L. Rivat, J. Dodinval-Versie, H.W. Goedde, Ruth G. Wiens, E. Defrise-Gussenhoven, Elvir Lander, M.G. Polczer, P Moureau, L. Beckman, A. Arndt-Hanser, H.H. Kornhuber, P. Dodinval, H. Walter, R.K. Sakai, L.N. Went, Hans Olof Åkesson, C. Ropartz, Francisco M. Salzano, P.A. Parsons, P.-Y. Rousseau, F.M. Johnson, H. Baitsch, Hans Forssman, Frederick R. Sergovich, J.L. Woods, J. Dichgans, R. Malchair, and E. Andresen

Subjects
Genetics, Genetics (clinical)
Published
1964

9. Buchbesprechungen – Book Reviews – Livres nouveaux

Author

J. Dichgans, R. Malchair, R.K. Sakai, Ruth G. Wiens, F.M. Johnson, A. Arndt-Hanser, J.L. Woods, Hans Forssman, Mary Whittaker, P. Dodinval, L. Rivat, P Moureau, L. Beckman, Francisco M. Salzano, P.-Y. Rousseau, H. Baitsch, E. Andresen, H. Walter, J. Dodinval-Versie, L.N. Went, E. Defrise-Gussenhoven, Hubert C. Soltan, M.G. Polczer, H.H. Kornhuber, P. Adler, W. Bernhard, H.W. Goedde, Hans Olof Åkesson, C. Ropartz, P.A. Parsons, Frederick R. Sergovich, and Elvir Lander

Subjects
Genetics, Genetics (clinical)
Published
1964

12. Index rerum ad Vol. 14

Author

P Moureau, L. Beckman, H.W. Goedde, Mary Whittaker, L. Rivat, Elvir Lander, F.M. Johnson, H. Baitsch, H.H. Kornhuber, J. Dichgans, Hans Olof Åkesson, R. Malchair, P. Dodinval, A. Arndt-Hanser, Frederick R. Sergovich, J.L. Woods, L.N. Went, W. Bernhard, Hans Forssman, E. Andresen, R.K. Sakai, C. Ropartz, P.A. Parsons, H. Walter, E. Defrise-Gussenhoven, Hubert C. Soltan, Francisco M. Salzano, P.-Y. Rousseau, M.G. Polczer, J. Dodinval-Versie, P. Adler, and Ruth G. Wiens

Subjects
Genetics, Genetics (clinical)
Published
1964

13. Buchbesprechungen – Book Reviews – Livres Nouveaux / Varia

Author

C. Kousmine, A. Schnitzer, Hedi Fritz-Niggli, A. Vogel, E. Glatthaar, H. Steiner, Peter Sträuli, A. L. Meier, Werner Brunner, W. Bernhard, M. Allgöwer, P. Loustalot, W. Hess, Giovanni Lotti, M. Strojewski, A. Walser, Robert Schobinger, P. Spring, A. Labhart, and H.J. Wespi

Subjects
Cancer Research, Oncology, General Medicine
Published
1958

14. Index autorum ad Vol. 14

Author

Ruth G. Wiens, Elvir Lander, Mary Whittaker, L. Rivat, P Moureau, L. Beckman, F.M. Johnson, Frederick R. Sergovich, Francisco M. Salzano, P.-Y. Rousseau, Hans Olof Åkesson, Hans Forssman, A. Arndt-Hanser, E. Defrise-Gussenhoven, J. Dichgans, W. Bernhard, J.L. Woods, C. Ropartz, P. Dodinval, E. Andresen, R.K. Sakai, P.A. Parsons, R. Malchair, M.G. Polczer, H. Baitsch, H.H. Kornhuber, Hubert C. Soltan, L.N. Went, H.W. Goedde, H. Walter, P. Adler, and J. Dodinval-Versie

Subjects
Index (economics), Statistics, Genetics, Genetics (clinical), Mathematics
Published
1964

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