Search

Your search keyword '"T B, Shows"' showing total 5 results
Start Over Author "T B, Shows" Publisher s. karger ag
5 results on '"T B, Shows"'

3. Mapping AK1 ACONs, and AK3 to chromosome 9 in man employing an X/9 translocation and somatic cell hybrids

Author

T B Shows and J A Brown

Subjects
Genetics, Somatic Cell Hybrids, Adenylate kinase, Locus (genetics), Chromosome 9, Chromosomal translocation, Biology, Molecular biology, Family studies, ABO blood group system, Molecular Biology, Gene, Genetics (clinical)
Abstract

The adenylate kinase1 (AK1), adenylate kinase3 (AK3), and aconitases (ACON3) genes have been assigned to chromosome 9 in man by employing an X/9 translocation segregating in man-mouse somatic cell hybrids. Segregation was controlled by taking advantage of the HAT/8-azaguanine selection-counterselection strategy directed at the X-linked HPRT locus. Assignment of AK1to chromosome 9 has suggested the assignment of the ABO blood-group locus and the nail-patella (Np) locus to 9, since both loci are linked to AK1by family studies.

Published
1977
Full Text
View/download PDF

4. Genetic mapping of the human polymeric immunoglobulin receptor gene to chromosome region 1q31→q41

Author

T B Shows, R.L. Eddy, M M Le Beau, M. Kingzette, M.K. Davidson, W.C. Hanly, and L.A. DiPietro

Subjects
Restriction Mapping, Hybrid Cells, Immunoglobulin E, Gene mapping, Cell surface receptor, Sequence Homology, Nucleic Acid, Genetics, Humans, Cloning, Molecular, Receptors, Immunologic, Molecular Biology, Gene, Metaphase, Genetics (clinical), biology, Chromosome Mapping, Membrane transport, Molecular biology, Secretory Component, Blotting, Southern, Chromosomes, Human, Pair 1, Paracellular transport, biology.protein, Antibody, Oligonucleotide Probes, Polymeric immunoglobulin receptor
Abstract

Polymeric immunoglobulin receptor (PIGR) is a transmembrane glycoprotein which is expressed by epithelial cells and is involved in the transcellular transport of polymeric immunoglobulins into secretions. We cloned the human gene for PIGR and used the clone to obtain probes to determine the chromosomal localization of PIGR. Analysis of somatic cell hybrids and in situ chromosomal hybridization localized the human PIGR gene locus to 1q31→q41.

Published
1988
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results