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Your search keyword '"Shigeru Okuya"' showing total 2 results
Start Over Author "Shigeru Okuya" Publisher s. karger ag
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2. Myelofibrosis and Systemic Lupus erythematosus: Reversal of Fibrosis with High-Dose Corticosteroid Therapy

Author

Toshio Kaneko, Yasushi Inoue, Shigeru Okuya, Koichiro Okafuji, Atsushi Matsubara, and Kohei Kaku

Subjects
Adult, medicine.medical_specialty, Systemic disease, medicine.drug_class, Biopsy, medicine.medical_treatment, Hemorrhagic Disorders, Methylprednisolone, Gastroenterology, Bone Marrow, immune system diseases, Internal medicine, Humans, Lupus Erythematosus, Systemic, Medicine, skin and connective tissue diseases, Myelofibrosis, Chemotherapy, business.industry, Anemia, Hematology, General Medicine, medicine.disease, Thrombocytopenia, medicine.anatomical_structure, Primary Myelofibrosis, Immunology, Prednisolone, Corticosteroid, Female, Bone marrow, business, Anti-SSA/Ro autoantibodies, medicine.drug
Abstract

A case of myelofibrosis in association with systemic lupus erythematosus (SLE) is reported. Acute thrombocytopenia and a bleeding tendency developed in a 24-year-old woman with SLE. Bone marrow aspiration was unsuccessful due to myelofibrosis. Pulse therapy with methylprednisolone reversed both thrombocytopenia and myelofibrosis. A review of the literature revealed that the coexistence of SLE and myelofibrosis is a rare occurrence. Only 7 cases, to our knowledge, have ever been reported in detail. The present case is the 3rd in which myelofibrosis was reversed by corticosteroids.

Published
1992

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