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11 results on '"S. Béguin"'

1. Title Page / Table of Contents / Preface

Author

Benvindo Justiça, E. Segalés, Gloria Saccani, Evy Bashardi, Andrew N. Nicolaides, Armando Tripodi, T. Fenyvesi, G. Origliani, J. Vermylen, R. Rossi, A. Nemmar, Alexander Koshkaryev, Silvia Navarro, S. Béguin, Francesco Violi, Tiziana Garofano, Antonella Tufano, Uri Seligsohn, Fabrizio Fabris, H.C. Hemker, G. Vilahur, Franco Semprini, R. Abbate, S. Fedi, Saul Yedgar, Sara Morais, C. Fatini, Licia Iacoviello, Irène Juhan-Vague, F. Gensini, Helga Grafenhofer, P. Giesen, S. Coccheri, B. Nemery, P. Carrasco, T. Grimaldi, Jacqueline Conard, G. Fantini, Ida Martinelli, Chiara Melloni, F.R. Rosendaal, Francesco Fallani, Gordon D.O. Lowe, E. Sticchi, Mónica Pereira, Joseph Loscalzo, J.I. Abad, V. Regnault, Juan Carlos Souto, T. Lecompte, Gregory Barshtein, Giovanni Romeo, V.V. Kakkar, Ingrid Pabinger, Ebrahim Shah, Giovanni Di Minno, A. De Fabritiis, F. Sofi, Pilar Medina, Alexandra Estevinho, Matteo Nicola Dario Di Minno, Justo Aznar, E. Conti, Grigoris T. Gerotziafas, George Geroulakos, E. de Smed, Maria Assunta Silvestri, Giuseppe G. Nenci, Fabio M. Pulcinelli, Luisa Lenti, Ismail Elalamy, B. Cosmi, Pierre Morange, Amparo Estellés, Angelo Branzi, Marie-Christine Alessi, Andrew H. Baker, Roberto Catasca, Raymond Verhaeghe, Samuele Nanni, V. Llorente, Francisco España, Andrea Ghiselli, F. Coppi, Domenico Prisco, Manuel Campos, M.F. Hoylaerts, P. Poredoš, Meyer Michel Samama, Stavros K. Kakkos, Giovanni Melandri, José Miguel P. Ferreira de Oliveira, Maura Griffin, David A. Lane, R. AlDieri, Augusto Di Castelnuovo, Serenella Rotondo, L. Badimon, J.J. Badimon, Giovanna Marchetti, Antonella Marcoccia, M.G. Modena, Henrik Sillesen, Joseph Emmerich, Daniela Turchetti, Luigina R. Mollica, Giovanni de Gaetano, Rossella Marcucci, Maria Benedetta Donati, José Manuel Cabeda, Pasquale Pignatelli, Giuseppe Germanò, Pierluigi Tricoci, J. Harenberg, Marie Hélène Horellou, Gianni Belcaro, Antonio Girolami, Bruno Girolami, R. Wagenvoord, Francesco Bernardi, M. Verstraete, P.M. Mannucci, Jean-Noël Fiessinger, I. Jörg, and Irene Pereira

Subjects
medicine.medical_specialty, business.industry, Physiology (medical), medicine, Table of contents, Hematology, Title page, business, Classics, Surgery
Published
2003

2. On the Coagulation of Platelet-Rich Plasma

Author

I. Keularts and S. Béguin

Subjects
biology, Chemistry, Hirudin, Hematology, Pharmacology, Platelet membrane glycoprotein, Thrombomodulin, Fibrin, Thrombin, Physiology (medical), medicine, biology.protein, Glycoprotein Ib-IX-V Receptor Complex, Platelet, Platelet activation, circulatory and respiratory physiology, medicine.drug
Abstract

Thrombin formation and blood platelet reactions are intimately linked in haemostasis and in thrombosis. In vivo, procoagulant phospholipids required for the coagulation mechanism are mainly provided by activated platelets, and thrombin is the most potent platelet activator. To study these interactions, an ancient tool of coagulation physiology, the thrombin generation test, was revived and the results obtained were reviewed. The amount of thrombin activity that develops, expressed as the endogenous thrombin potential (the area under the thrombin generation curve), is influenced by the clotting factors (except XII and XIII), the activated protein C system and natural inhibitors on the one hand and by platelet activity on the other. The platelet reactions that we found to be involved are induced by thrombin via glycoprotein (GP) IIb/IIIa activation and by fibrin via interaction with GPIb. von Willebrand factor is crucial in both reactions and therefore an obligatory factor for normal thrombin generation in the presence of platelets. All antithrombotics, be it anticoagulants (e.g. OAC, all heparins or hirudin) or antiplatelet drugs (aspirin, GPIIb/IIIa blockers) diminish thrombin generation.

Published
1999

3. Title Page / Table of Contents, Vol. 20, Supplement 1, 1990

Author

P.G. Settembrini, I. Caramazza, Rosanna Abbate, Anna Maria Gori, K.-H. Usadel, G. Coggi, Sergio Coccheri, Valentin Fuster, R. Codemo, Domenico Prisco, Colin R. M. Prentice, Pietro Amedeo Modesti, H.C. Hemker, J. Harenberg, G. Zoppetti, Rita Paniccia, Monica Attanasio, G.G. Neri Semen, M. Lettino, K. Mall, A.L. Bloom, S. Roveri, G. Talarico, G. Galli, P. Prandoni, D.L. Heene, H. Bratsch, G. Stehle, F.A. Ofosu, Marc Verstraete, Ira M. Herman, E. Ambrosioni, M. Vigo, M. Bossi, N. Olivari, R. Lamberti, Ulf Lindahl, K.T. Preissner, G. Pezzuoli, Francesca Martini, Domenico Inzitari, Ilaria Cecioni, G. Andriuoli, E. Strocchi, K. Huck, Francesco Bonechi, A. Lotto, G.G. Neri Serneri, Luigi Amaducci, Alberto Fortini, S. Béguin, A.M. Cattelan, Luigi Tavazzi, B. Casu, G.F. Gensini, A. Ruol, G. Fratianni, G. Negri, Marc Cohen, Andrea Colella, A. Colombo, Betti Giusti, M. Blauth, Patricia A. D’Amore, and Ce. Dempfle

Subjects
business.industry, Physiology (medical), Library science, Medicine, Table of contents, Hematology, business, Title page
Published
1990

4. Contents Vol. 32, 2002

Author

Giovanna Marchetti, Antonella Marcoccia, Domenico Prisco, Giovanni Melandri, J.J. Badimon, Mónica Pereira, Justo Aznar, Angelo Branzi, Roberto Catasca, Francesco Violi, Licia Iacoviello, P.M. Mannucci, Andrew N. Nicolaides, Jean-Noël Fiessinger, Francisco España, Gregory Barshtein, Fabrizio Fabris, Luisa Lenti, Maria Assunta Silvestri, Matteo Nicola Dario Di Minno, S. Coccheri, Samuele Nanni, F. Coppi, F.R. Rosendaal, T. Fenyvesi, Alexander Koshkaryev, M.F. Hoylaerts, Luigina R. Mollica, Andrea Ghiselli, Alexandra Estevinho, A. De Fabritiis, Silvia Navarro, P. Poredoš, Irène Juhan-Vague, H.C. Hemker, Pierluigi Tricoci, José Manuel Cabeda, R. Abbate, G. Vilahur, Antonella Tufano, P. Carrasco, S. Fedi, J. Harenberg, Tiziana Garofano, Fabio M. Pulcinelli, M.G. Modena, Saul Yedgar, Juan Carlos Souto, Henrik Sillesen, B. Cosmi, Meyer Michel Samama, Raymond Verhaeghe, Ingrid Pabinger, P. Giesen, Ebrahim Shah, Pasquale Pignatelli, Giuseppe Germanò, David A. Lane, Jacqueline Conard, Augusto Di Castelnuovo, T. Grimaldi, Pierre Morange, Marie-Christine Alessi, José Miguel P. Ferreira de Oliveira, Daniela Turchetti, Gloria Saccani, V. Regnault, Joseph Emmerich, Giovanni de Gaetano, Rossella Marcucci, Maria Benedetta Donati, Manuel Campos, J. Vermylen, Marie Hélène Horellou, Ida Martinelli, Serenella Rotondo, R. AlDieri, E. Sticchi, Giuseppe G. Nenci, F. Sofi, Sara Morais, Helga Grafenhofer, F. Gensini, C. Fatini, Chiara Melloni, Franco Semprini, R. Wagenvoord, Francesco Bernardi, M. Verstraete, I. Jörg, Grigoris T. Gerotziafas, Gianni Belcaro, Antonio Girolami, Bruno Girolami, Gordon D.O. Lowe, Joseph Loscalzo, Giovanni Romeo, V.V. Kakkar, Giovanni Di Minno, Irene Pereira, Benvindo Justiça, Ismail Elalamy, T. Lecompte, G. Fantini, Francesco Fallani, Pilar Medina, V. Llorente, L. Badimon, E. Conti, Armando Tripodi, G. Origliani, R. Rossi, Stavros K. Kakkos, Maura Griffin, George Geroulakos, E. de Smed, A. Nemmar, Amparo Estellés, Andrew H. Baker, Uri Seligsohn, B. Nemery, S. Béguin, J.I. Abad, E. Segalés, and Evy Bashardi

Subjects
medicine.medical_specialty, business.industry, Physiology (medical), General surgery, medicine, Hematology, business, Surgery
Published
2002

5. Subject Index, Vol. 20, 1990

Author

K.-H. Usadel, Ira M. Herman, J. Harenberg, Sergio Coccheri, G. Pezzuoli, G. Andriuoli, Anna Maria Gori, Pietro Amedeo Modesti, G.G. Neri Serneri, E. Ambrosioni, K. Mall, E. Strocchi, Alberto Fortini, S. Roveri, Rita Paniccia, A. Colombo, Valentin Fuster, N. Olivari, G. Talarico, A. Lotto, Rosanna Abbate, A.L. Bloom, M. Lettino, Betti Giusti, M. Bossi, Francesco Bonechi, R. Lamberti, Ulf Lindahl, G.G. Neri Semen, Colin R.M. Prentice, Francesca Martini, K.T. Preissner, K. Huck, H.C. Hemker, B. Casu, G. Coggi, M. Blauth, M. Vigo, Marc Cohen, Domenico Prisco, Ce. Dempfle, R. Codemo, G. Stehle, Luigi Amaducci, Marc Verstraete, S. Béguin, Monica Attanasio, G. Zoppetti, P.G. Settembrini, G. Galli, Andrea Colella, P. Prandoni, Ilaria Cecioni, I. Caramazza, Patricia A. D’Amore, G.F. Gensini, A.M. Cattelan, F.A. Ofosu, D.L. Heene, A. Ruol, G. Fratianni, Domenico Inzitari, Luigi Tavazzi, G. Negri, and H. Bratsch

Subjects
medicine.medical_specialty, Index (economics), business.industry, Physiology (medical), Physical therapy, medicine, Physiology, Subject (documents), Hematology, business
Published
1990

6. Contents, Vol. 19, 1989

Author

Peter Baumann, Utako Okamoto, L. Stigendahl, Junichiro Yamamoto, Thomas Jürgensen, Roberto Quintavalla, M. Jeran, Zoltán Boda, S. Bjoern, M. Paolicelli, Duncan P. Thomas, Ulla Hedner, R. Ádány, Kálmán Rák, Peter H. Domer, Y. Okada, C. Manotti, György Pfliegler, A. Tóth, László Muszbek, Y. Nagamatsu, H.C. Hemker, Z. Papp, S. Béguin, A.G. Dettori, Y. Tsuda, Hau C. Kwaan, M. Pini, Jolan Harsfalvi, Trevor W. Barrowcliffe, István Tornai, Ma Xi, S.S. Bernvil, Claus-Ch. Heuck, and L. Tengborn

Subjects
Physiology (medical), Hematology
Published
1989

7. A New Variant of Human Prothrombin: Prothrombin Metz, Demonstration in a Family Showing Double Heterozygosity for Congenital Hypoprothrombinemia and Dysprothrombinemia

Author

S. Béguin, F. Josso, and Y. Rio

Subjects
Adult, Male, Heterozygote, Double heterozygosity, Biology, Hemorrhagic Disorders, Thrombin, Physiology (medical), Genetic variation, medicine, Humans, Child, Hypoprothrombinemias, Dysprothrombinemia, Genetics, Antithrombin, Genetic Variation, Heterozygote advantage, Hematology, medicine.disease, Pedigree, Prothrombin Metz, Kinetics, Female, Prothrombin, France, Hypoprothrombinemia, circulatory and respiratory physiology, medicine.drug
Abstract

Investigation of a mild hemorrhagic tendency in a French family revealed the father to be heterozygous for hypoprothrombinemia while the mother was heterozygous for dysprothrombinemia. All possible genetic combinations could be demonstrated. Among the children the double heterozygosity encountered in 3 of them allowed us to discover an abnormal prothrombin, prothrombin Metz, which generates an abnormal thrombin less sensitive to inactivation by antithrombin III than normal thrombin.

Published
1982

8. Importance of factor-IX-dependent prothrombinase formation - the Josso Pathway,- in clotting plasma

Author

H.C. Hemker, Ma Xi, S. Béguin, and Biochemie

Subjects
Chemistry, Phospholipid, Thrombin, Hematology, Plasma, Hemophilia A, Hemophilia B, Thromboplastin, chemistry.chemical_compound, Coagulation, Prothrombinase, hemic and lymphatic diseases, Physiology (medical), Immunology, Biophysics, medicine, Humans, Blood Coagulation, Phospholipids, circulatory and respiratory physiology, medicine.drug, Factor IX
Abstract

We report a study on the importance of factor IX activation in thromboplastin-dependent coagulation in plasma. Diluted, CaCl2-containing thromboplastin solutions at constant phospholipid concentration were used to trigger the coagulation in plasma from patients with congenital factor IX and factor VIII deñciency in the presence and absence of added factors IX and VIII, and the generation of thrombin activity was monitored. When coagulation is triggered with the high thromboplastin concentrations normally used in clinical routine tests, the generation of thrombin activity in plasma of patients with congenital factor IX deficiency before and after reconstitution with purified factor IX appears identical. When, however, coagulation is triggered with low thromboplastin concentrations, a clear dependency of the generation of thrombin activity on the concentration of factor IX becomes evident at factor IX concentrations lower than 30 nM (about 40% clotting factor activity). Factor VIII is a compulsory cofactor for this factor IX activity because the prothrombinase activity at optimal factor IX concentration is still critically dependent upon the amount of factor VIII present. The lower the amount of thromboplastin, the higher the importance of factor IX and factor VIII activation in thromboplastin-dependent coagulation. This suggests a role of this pathway in pathophysiological thrombin formation.

Published
1989

9. Subject Index, Vol. 19, 1989

Author

M. Paolicelli, Y. Okada, C. Manotti, A. Tóth, Y. Nagamatsu, Zoltán Boda, Ma Xi, R. Ádány, Hau C. Kwaan, Ulla Hedner, Peter Baumann, György Pfliegler, István Tornai, S.S. Bernvil, A.G. Dettori, Z. Papp, Trevor W. Barrowcliffe, Y. Tsuda, L. Stigendahl, M. Pini, Junichiro Yamamoto, László Muszbek, L. Tengborn, H.C. Hemker, Claus-Ch. Heuck, Kálmán Rák, S. Bjoern, S. Béguin, Utako Okamoto, M. Jeran, Thomas Jürgensen, Roberto Quintavalla, Jolan Harsfalvi, Duncan P. Thomas, and Peter H. Domer

Subjects
medicine.medical_specialty, Index (economics), business.industry, Physiology (medical), medicine, Physical therapy, Subject (documents), Hematology, business, Surgery
Published
1989

10. Book Review / Announcement

Author

Kálmán Rák, S. Béguin, Duncan P. Thomas, A. Tóth, Peter H. Domer, Y. Nagamatsu, Utako Okamoto, László Muszbek, H.C. Hemker, L. Stigendahl, Peter Baumann, Junichiro Yamamoto, S. Bjoern, Claus-Ch. Heuck, Y. Tsuda, Ma Xi, Roberto Quintavalla, Trevor W. Barrowcliffe, L. Tengborn, Ulla Hedner, M. Pini, István Tornai, S.S. Bernvil, Y. Okada, Thomas Jürgensen, Zoltán Boda, Hau C. Kwaan, Z. Papp, Jolan Harsfalvi, György Pfliegler, R. Ádány, A.G. Dettori, M. Paolicelli, M. Jeran, and C. Manotti

Subjects
medicine.medical_specialty, business.industry, Physiology (medical), General surgery, Medicine, Hematology, business, Surgery
Published
1989

11. Subject Index, Vol. 12, 1982

Author

S. Béguin, F.H. Herrmann, M. Meyer, E. Ihle, Y. Rio, Arne Nordøy, F. Josso, A.M.A. Gader, M. Verstraete, and Jan Brox

Subjects
medicine.medical_specialty, Index (economics), business.industry, Physiology (medical), Physical therapy, Medicine, Subject (documents), Hematology, business, Surgery
Published
1982

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