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1. Contents Vol. 43, 2009

Author

Frasko R, Chalbi Belkahia, E. Plouvier, F. Thuillier, V. Rumenjak, Xavier Forceville, Volker Huge, A. Combes, D. Ben Saîd, Michael Vogeser, R. Ben Ali, Manfred Thiel, Dražen Vnuk, Nadia Kourda, Alexander Choukèr, V. Mostert, A. Castagnoli, Emna Gaïes, M.T. Oruç, Fabio Davoli, P. Le Toumelin, Wieland Raue, U. Han, Anis Klouz, Patrizia Campolongo, Jens Hartmann, P. Maruna, Jury Brandolini, D. Vitoux, Josip Kos, Z. Krstonijević, Mohamed Lakhal, Benedetta Bedetti, Daniela Hauer, Ž. Rašić, F. Sellitri, Jaroslav Lindner, N. Elkadri, V. Nesek-Adam, Gustav Schelling, Giampiero Dolci, A. Bloch, Franco Stella, M.M. Özmen, A. Pierantoni, Charalambos Menenakos, Nikolaos Tsilimparis, Ines Kaufmann, and M. Dehoux

Subjects
Traditional medicine, business.industry, Physiology, Medicine, Surgery, business
Published
2009

2. Malignant Melanoma Metastasis as a Cause of Small-Bowel Perforation

Author

Nikolaos Tsilimparis, Chris Braumann, Jens Hartmann, Charalampos Menenakos, and P. Rogalla

Subjects
Adult, Male, Oncology, Cancer Research, medicine.medical_specialty, Pathology, Skin Neoplasms, Intestinal Neoplasm, Bowel perforation, Metastasis, Internal medicine, Intestinal Neoplasms, Intestine, Small, medicine, Humans, Melanoma, neoplasms, Melanoma diagnosis, business.industry, Incidence (epidemiology), Hematology, General Medicine, medicine.disease, Intestinal Perforation, Lymph, business, Small bowel perforation
Abstract

Malignant melanoma is a disease with an increasing rate of incidence, currently at 10 cases per 100,000. In most cases, malignant melanoma metastasizes over the lymph vessels to parenchymal organs. Symptomatic metastases are found in the gastrointestinal tract in only about 2% of the patients.A 43-year-old patient with a known metastasized malignant melanoma (brain, liver, bones) was admitted to the department of dermatology due to fatigue, headache and unspecified abdominal symptoms. Because of persistent abdominal symptoms, a computed tomography (CT) scan of the abdomen was performed, showing a perforation of the ileum with an abscess on the basis of multiple small-bowel metastases. A segmental small-bowel resection with primary anastomosis was performed. The postoperative course of the patient was complicated by a subcutaneous wound infection and a prolonged period of convalescence (due to multiple brain metastases).Novel therapy concepts and medication in the treatment of patients with malignant melanoma have improved life expectancy. These patients are therefore expected to suffer more frequently from complications of the primary disease. Interdisciplinary management and cooperation is required to adequately diagnose and handle such cases.

Published
2009

3. Subject Index Vol. 43, 2009

Author

Wieland Raue, U. Han, M. Dehoux, Patrizia Campolongo, Dražen Vnuk, Ines Kaufmann, Benedetta Bedetti, Manfred Thiel, Xavier Forceville, Emna Gaïes, A. Combes, D. Ben Saîd, M.T. Oruç, R. Ben Ali, Jury Brandolini, Nikolaos Tsilimparis, A. Bloch, Volker Huge, Nadia Kourda, P. Maruna, Josip Kos, Franco Stella, V. Mostert, Michael Vogeser, A. Castagnoli, Jens Hartmann, M.M. Özmen, Gustav Schelling, Giampiero Dolci, Z. Krstonijević, N. Elkadri, P. Le Toumelin, F. Thuillier, Ž. Rašić, Fabio Davoli, D. Vitoux, F. Sellitri, E. Plouvier, A. Pierantoni, Jaroslav Lindner, Anis Klouz, V. Nesek-Adam, Alexander Choukèr, Daniela Hauer, Mohamed Lakhal, Charalambos Menenakos, Frasko R, Chalbi Belkahia, and V. Rumenjak

Subjects
Gerontology, Index (economics), Surgery, Subject (documents), Psychology
Published
2009

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