1. COLOR: A Randomized Clinical Trial Comparing Laparoscopic and Open Resection for Colon Cancer
- Author
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Stephan Wildi, H. Lippert, Hajime Maeta, Takashi Maeba, Shinichi Yachida, Luis Ortiz de Zárate, Thomas Kotsis, Levent Tezcan, Sadık Perek, Kimberley Giffard, K. Thon, Emre F. Yekebas, Javier Osorio, Ahmet Batkin, H. Stöltzing, Sasan Najibi, V. Zolota, Ola Røkke, V. Patrinou, Haldun Uluutku, Shawn M. Garber, Hisao Wakabayashi, Matthew G. Cohen, Esperanza Bachs, Mehmet Levhi Akin, Joseph Espat, Jean-Jacques Tuech, Núria Farreras, Moshe Schein, Asiye Perek, Metin Kapan, Sukru Yildirim, M.R.B. Keighley, Idunn Nesvik, Peter Lehocky, Agathi Paphiti, T. Manger, Nib Soehendra, Jean-Pierre Arnaud, Xavier Rogiers, G. Skroubis, Dionysios Voros, Christoph Busch, Bernhard Egger, Ronald S. Chamberlain, Charles Sklar, Jason P. Shaw, Leslie H. Blumgart, Cengiz Erenoglu, Julie Miller, Olof Winzer, C. Vagianos, Jonathan S. Zager, Michael G. Sarr, Elias Mallas, M. Pross, Stefan W. Schmid, Markus Naef, C. Haeckel, Eric R. Frykberg, Ian K. Komenaka, Ertuğrul Göksoy, Karl Søndenaa, Jules E. Garbus, Jakob R. Izbicki, A. Buttafuoco, Patrick Pessaux, Markus W. Büchler, and Matrona Frangou
- Subjects
Male ,Laparoscopic surgery ,medicine.medical_specialty ,Colorectal cancer ,medicine.medical_treatment ,Malignancy ,law.invention ,Randomized controlled trial ,Colon, Sigmoid ,law ,Open Resection ,medicine ,Humans ,Laparoscopic resection ,Prospective Studies ,Laparoscopy ,Colectomy ,Aged ,medicine.diagnostic_test ,business.industry ,fungi ,Gastroenterology ,food and beverages ,Cancer ,medicine.disease ,Surgery ,Europe ,Sigmoid Neoplasms ,Colonic Neoplasms ,Female ,business - Abstract
Background: Laparoscopic surgery has proven to be safe and effective. However, the value of laparoscopic resection for malignancy in terms of cancer outcome can only be assessed by large prospective randomized clinical trials with sufficient follow-up. Methods: COLOR (COlon carcinoma Laparoscopic or Open Resection) is a European multicenter randomized trial which has started in September 1997. In 24 hospitals in Sweden, The Netherlands, Germany, France, Italy and Spain, 1,200 patients will be included. The primary end point of the study is cancer-free survival after 3 years. Results: Within Conclusions: Although laparoscopic surgery appears of value in colorectal malignancy, results of randomized trials have to be awaited to determine the definitive place of laparoscopy in colorectal cancer. Considering the current accrual rate, the COLOR study will be completed in 2002.
- Published
- 2000
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