1. Hemodialysis Decreases the Etiologically-Related Early Vascular Aging Observed in End-Stage Renal Disease: A 5-Year Follow-Up Study.
- Author
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Bia D, Galli C, Zócalo Y, Valtuille R, Wray S, Armentano R, and Cabrera-Fischer E
- Subjects
- Aging, Carotid Arteries physiopathology, Case-Control Studies, Femoral Artery physiopathology, Follow-Up Studies, Humans, Kidney Failure, Chronic complications, Pulse Wave Analysis methods, Kidney Failure, Chronic therapy, Renal Dialysis
- Abstract
Aims: To analyze the early vascular aging (EVA) in end-stage renal disease (ESRD) patients, attempting to determine a potential association between EVA and the etiology of ESRD, and to investigate the association of hemodialysis and EVA in ESRD patients during a 5-year follow-up period., Methods: Carotid-femoral pulse wave velocity (cfPWV) was obtained in 151 chronically hemodialyzed patients (CHP) and 283 control subjects, and in 25 CHP, who were followed-up after a 5-year lapse., Results: cfPWV increased in ESRD patients compared to control subjects. The cfPWV-age relationship was found to have a steeper increase in ESRD patients. The highest cfPWV and EVA values were observed in patients with diabetic nephropathy. Regression analysis demonstrated a significant reduction of the EVA in HD patients on a 5-year follow-up., Conclusion: Patients in ESRD showed higher levels of EVA. cfPWV and EVA differed in ESRD patients depending on their renal failure etiology. CHP showed an EVA reduction after a 5-year follow-up period., (© 2016 S. Karger AG, Basel.)
- Published
- 2017
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