1. Surgical treatment of hypothalamic hamartoma and refractory seizures: a case report and review of the literature.
- Author
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Kramer U, Spector S, Nasser W, Siomin V, Fried I, and Constantini S
- Subjects
- Child, Preschool, Consanguinity, Diagnosis, Differential, Electroencephalography, Epilepsy, Reflex etiology, Epilepsy, Reflex genetics, Hamartoma diagnosis, Hamartoma genetics, Humans, Hypothalamic Diseases diagnosis, Hypothalamic Diseases genetics, Hypothalamus pathology, Hypothalamus surgery, Magnetic Resonance Imaging, Male, Telemetry, Video Recording, Epilepsy, Reflex surgery, Hamartoma surgery, Hypothalamic Diseases surgery, Laughter
- Abstract
Refractory gelastic seizures are often associated with hypothalamic hamartoma (HH). Presurgical evaluation in such children often points to a distinct cortical region as the source of the seizures. A case of a child with HH and refractory seizures is presented. Video-EEG monitoring revealed a well-defined epileptic focus in the left frontal region. In accordance with the current understanding of the nature of hamartoma-related seizures, the hamartoma was resected. Follow-up evaluations revealed a marked improvement in seizure frequency and global functioning.
- Published
- 2001
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