1. 'Click chemistry'en route to pseudo-starch
- Author
-
Laurence Marmuse, Robert A. Field, and Sergey A. Nepogodiev
- Subjects
Magnetic Resonance Spectroscopy ,Starch ,Molecular Sequence Data ,Organic Chemistry ,Nuclear magnetic resonance spectroscopy ,Maltose ,Biochemistry ,Combinatorial chemistry ,Cycloaddition ,chemistry.chemical_compound ,Carbohydrate Sequence ,chemistry ,Click chemistry ,Physical and Theoretical Chemistry - Abstract
Rapid assembly of starch fragment analogues was achieved using "click chemistry". Specifically, two hexadecasaccharide mimics containing two parallel maltoheptaosyl chains linked via [1,2,3]-triazoles to a maltose core were synthesized using Cu(i)-catalyzed [3 + 2] dipolar cycloaddition of azido saccharides and 6,6'- and 4',6'-dipropargylated p-methoxyphenyl maltoside.
- Published
- 2005