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Your search keyword '"Comes-Franchini, Mauro"' showing total 16 results
Start Over Author "Comes-Franchini, Mauro" Publisher royal society of chemistry (rsc)
16 results on '"Comes-Franchini, Mauro"'

8. The one-step synthesis and surface functionalization of dumbbell-like gold–iron oxide nanoparticles: a chitosan-based nanotheranostic system

Author

Kostevsek, Nina, primary, Locatelli, Erica, additional, Garrovo, Chiara, additional, Arena, Francesca, additional, Monaco, Ilaria, additional, Nikolov, Ivaylo Petrov, additional, Sturm, Saso, additional, Zuzek Rozman, Kristina, additional, Lorusso, Vito, additional, Giustetto, Pierangela, additional, Bardini, Paola, additional, Biffi, Stefania, additional, and Comes Franchini, Mauro, additional

Published
2016
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14. Maghemite-containing PLGA–PEG-based polymeric nanoparticles for siRNA delivery: toxicity and silencing evaluation

Author

Maria Naddaka, Mauro Comes Franchini, Ella Kurlander, Shulamit Michaeli, Erica Locatelli, Emmanuel Lellouche, Liron L. Israel, Jean-Paul Lellouche, Lellouche, Emmanuel, Locatelli, Erica, Israel, Liron Limor, Naddaka, Maria, Kurlander, Ella, Michaeli, Shulamit, Lellouche, Jean-Paul, and Comes Franchini, Mauro

Subjects
Small interfering RNA, General Chemical Engineering, MRI contrast agent, Genetic enhancement, Maghemite, Nanotechnology, macromolecular substances, 02 engineering and technology, Gene delivery, engineering.material, 010402 general chemistry, 01 natural sciences, chemistry.chemical_compound, Gene silencing, Chemical Engineering (all), Chemistry (all), technology, industry, and agriculture, General Chemistry, 021001 nanoscience & nanotechnology, 0104 chemical sciences, chemistry, engineering, Biophysics, Magnetic nanoparticles, 0210 nano-technology, Ethylene glycol
Abstract

Gene therapy based on small interfering RNA (siRNA) has emerged as an exciting new therapeutic approach. In this work, incorporation of PEI into poly(d,l-lactide-co-glycolide)-poly(ethylene glycol) (PLGA-b-PEG) particles has been shown to be quite effective in the development of corresponding gene delivery systems, and encapsulation of magnetic nanoparticles as an MRI contrast agent, resulted in unique theranostic nanoparticles.

Published
2017
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15. The one-step synthesis and surface functionalization of dumbbell-like gold–iron oxide nanoparticles: a chitosan-based nanotheranostic system

Author

Paola Bardini, Nina Kostevšek, Ilaria Monaco, Stefania Biffi, Erica Locatelli, Ivaylo Nikolov, Chiara Garrovo, Kristina Zuzek Rozman, Mauro Comes Franchini, Sašo Šturm, Francesca Arena, Pierangela Giustetto, Vito Lorusso, Kostevsek, Nina, Locatelli, Erica, Garrovo, Chiara, Arena, Francesca, Monaco, Ilaria, Nikolov, Ivaylo Petrov, Sturm, Saso, Zuzek Rozman, Kristina, Lorusso, Vito, Giustetto, Pierangela, Bardini, Paola, Biffi, Stefania, and Comes Franchini, Mauro

Subjects
Materials science, Light, Surface Properties, Dumbbell like, Oxide, Metal Nanoparticles, Nanoparticle, Nanotechnology, One-Step, 02 engineering and technology, 010402 general chemistry, 01 natural sciences, Theranostic Nanomedicine, Catalysis, Photoacoustic Techniques, Chitosan, chemistry.chemical_compound, nanoparticles, theranostic, surface, Materials Chemistry, Particle Size, Molecular Structure, Metals and Alloys, General Chemistry, 021001 nanoscience & nanotechnology, Biocompatible material, Ferrosoferric Oxide, 0104 chemical sciences, Surfaces, Coatings and Films, Electronic, Optical and Magnetic Materials, Energy Transfer, chemistry, Ceramics and Composites, Surface modification, Gold, 0210 nano-technology, Iron oxide nanoparticles
Abstract

The first one-step synthesis of dumbbell-like gold–iron oxide nanoparticles has been reported here. Surface functionalization with a biocompatible chitosan matrix allowed us to obtain a novel targetable diagnostic and therapeutic tool.

Published
2016
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16. Surface modifications of gold nanorods for applications in nanomedicine

Author

Erica Locatelli, M. Comes Franchini, Ilaria Monaco, Locatelli, E, Monaco, I., and Comes Franchini, Mauro

Subjects
Materials science, General Chemical Engineering, Nanomedicine, Surface modification, Nanotechnology, Nanorod, General Chemistry, nanorods, coating, surface, nanomedicine
Abstract

Gold nanorods (GNRs) are appealing nanostructures for a wide variety of nanomedicine-based diagnostic and therapeutic approaches against untreatable diseases. Indeed, they possess unique and extraordinary optical features, which if conveniently stressed, would bring several benefits to non-invasive theranostic treatments. Major concerns regarding their practical application are derived not directly from GNRs but from molecules linked onto their surface, which could be source of toxicity as well as powerful allies for treatments' enhancement. Thus, specific and tailored surface modification of GNRs with several active moieties has become a crucial factor for their development. In this review, crucial breakthroughs and major possibilities deriving from the surface decoration of GNRs for final nanomedicine applications, as well as progress in therapy and diagnosis relying on the functionalization of these nanosystems will be summarized and discussed.

Published
2015
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